Evidence map›Paper›PMID 37896714›Full record

ArticleSensors (Basel, Switzerland)2023

Accelerometric Classification of Resting and Postural Tremor Amplitude.

Christina van der Linden, Thea Berger, Gregor A Brandt, Joshua N Strelow, Hannah Jergas, Juan Carlos Baldermann, Veerle Visser-Vandewalle, Gereon R Fink, Michael T Barbe, Jan Niklas Petry-Schmelzer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  7. Ultrasound-Informed State Estimation of Wrist Tremor Dynamics via Koopman Operator for Personalized Sensory Peripheral Nerve Stimulation.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Christina van der LindenDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.ORCID 0000-0003-2091-4638
Thea BergerDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Gregor A BrandtDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Joshua N StrelowDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.ORCID 0000-0002-2194-5930
Hannah JergasDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Juan Carlos BaldermannDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Veerle Visser-VandewalleDepartment of Stereotactic and Functional Neurosurgery, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Gereon R FinkDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.ORCID 0000-0002-8230-1856
Michael T BarbeDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Jan Niklas Petry-SchmelzerDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Till A DembekDepartment of Neurology, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.ORCID 0000-0001-7023-146X
University of Cologne · DEForschungszentrum Jülich · DE

Funding

Deutsche Forschungsgemeinschaft 502436811
6 · The paper itself

Abstract

Clinical rating scales for tremors have significant limitations due to low resolution, high rater dependency, and lack of applicability in outpatient settings. Reliable, quantitative approaches for assessing tremor severity are warranted, especially evaluating treatment effects, e.g., of deep brain stimulation (DBS). We aimed to investigate how different accelerometry metrics can objectively classify tremor amplitude of Essential Tremor (ET) and tremor in Parkinson's Disease (PD). We assessed 860 resting and postural tremor trials in 16 patients with ET and 25 patients with PD under different DBS settings. Clinical ratings were compared to different metrics, based on either spectral components in the tremorband or pure acceleration, derived from simultaneous triaxial accelerometry captured at the index finger and wrist. Nonlinear regression was applied to a training dataset to determine the relationship between accelerometry and clinical ratings, which was then evaluated in a holdout dataset. All of the investigated accelerometry metrics could predict clinical tremor ratings with a high concordance (>70%) and substantial interrater reliability (Cohen's weighted Kappa > 0.7) in out-of-sample data. Finger-worn accelerometry performed slightly better than wrist-worn accelerometry. We conclude that triaxial accelerometry reliably quantifies resting and postural tremor amplitude in ET and PD patients. A full release of our dataset and software allows for implementation, development, training, and validation of novel methods.

Indexed as

Essential TremorParkinson DiseaseAccelerometryHumansReproducibility of ResultsTremoraccelerometryessential tremorParkinson’s Diseasetremorwearables

Identifiers

PMID37896714
PMCPMC10611060
OpenAlexW4387843914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.