Evidence map›Paper›PMID 37896406›Full record

ArticlePolymers2023

Influence of Alginate Properties and Calcium Chloride Concentration on Alginate Bead Reticulation and Size: A Phenomenological Approach.

Chanez Bennacef, Stéphane Desobry, Jordane Jasniewski, Sébastien Leclerc, Laurent Probst, Sylvie Desobry-Banon

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

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  15. Rose Bengal-Chitosan Nanocomposites for Oral Administration.Nanomaterials (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chanez BennacefUniversité de Lorraine, Laboratoire d'Ingénierie des Biomolécules (LIBio), ENSAIA, 54000 Nancy, France.
Stéphane DesobryUniversité de Lorraine, Laboratoire d'Ingénierie des Biomolécules (LIBio), ENSAIA, 54000 Nancy, France.ORCID 0000-0002-8992-4845
Jordane JasniewskiUniversité de Lorraine, Laboratoire d'Ingénierie des Biomolécules (LIBio), ENSAIA, 54000 Nancy, France.ORCID 0000-0002-8822-1742
Sébastien LeclercUniversité de Lorraine, CNRS, LEMTA, Faculty of Science and Technology, 54000 Nancy, France.ORCID 0000-0003-0196-2271
Laurent ProbstCookal Company, 19 Avenue de la Meurthe, 54320 Maxéville, France.
Sylvie Desobry-BanonUniversité de Lorraine, Laboratoire d'Ingénierie des Biomolécules (LIBio), ENSAIA, 54000 Nancy, France.ORCID 0000-0001-9204-3435
Laboratoire d'Ingénierie des BiomoléculesCentre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche 15-004
6 · The paper itself

Abstract

Two types of alginates, AlgLF and AlgP, were used in this study to produce alginate beads by electro-vibratory extrusion. AlgLF and AlgP exhibited different Mannuronate/Guluronate (M/G) ratios and molecular weights as measured by NMR and SEC-MALS. The calcium chloride concentration was found to have the greatest effect on bead size. Higher concentrations resulted in smaller beads. AlgLF with a higher molecular weight and a lower proportion of G blocks showed smaller beads. For both alginates, the bead size was also influenced by the flow rate and vibration frequency. Alginate solution aging showed a minimal effect. Alginate reticulation was modeled using a mathematical equation. The study provides insights for the optimization of alginate-based materials in different applications by shedding light on the main factors influencing bead size. The importance of the molecular weight, M/G ratio and calcium ion concentration in the gelling process is highlighted, providing opportunities for the tailoring of alginate materials through a phenomenological model.

Indexed as

alginatealginate bead sizeionic gelationM/G ratiomodelingmolecular weightphenomenological modelresponse surface method

Identifiers

PMID37896406
PMCPMC10610877
OpenAlexW4387821913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.