Evidence map›Paper›PMID 37896265›Full record

ArticlePharmaceutics2023

Curcumin as a Stabilizer of Macrophage Polarization during

Maria Clara C Cordeiro, Fernanda D Tomé, Felipe S Arruda, Simone Gonçalves da Fonseca, Patrícia R A Nagib, Mara R N Celes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria Clara C CordeiroDepartment of Bioscience and Technology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia 74605-050, GO, Brazil.ORCID 0000-0003-4700-9646
Fernanda D ToméDepartment of Bioscience and Technology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia 74605-050, GO, Brazil.
Felipe S ArrudaDepartment of Bioscience and Technology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia 74605-050, GO, Brazil.ORCID 0000-0002-6775-390X
Simone Gonçalves da FonsecaDepartment of Bioscience and Technology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia 74605-050, GO, Brazil.ORCID 0000-0002-5126-6306
Patrícia R A NagibDepartment of Microbiology, Immunology and Parasitology, Biological Science Institute, Federal University of Juiz de Fora, Juiz de Fora 36036-900, MG, Brazil.ORCID 0000-0002-1331-0441
Mara R N CelesDepartment of Bioscience and Technology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia 74605-050, GO, Brazil.ORCID 0000-0002-4733-007X
Universidade Federal de Goiás · BRUniversidade Federal de Juiz de Fora · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior AUXPE n. 88881.845026/2023-01Fundação de Apoio a Pesquisa do Estado de Goiás Edital FAPEG n. 06/2018 - 201810267001566
6 · The paper itself

Abstract

Malaria is a parasitic infection responsible for high morbidity and mortality rates worldwide. During the disease, phagocytosis of infected red blood cells by the macrophages induces the production of reactive oxygen (ROS) and nitrogen species (RNS), culminating in parasite death. Curcumin (CUR) is a bioactive compound that has been demonstrated to reduce the production of pro-inflammatory cytokines and chemokines produced by macrophages but to reduce parasitemia in infected mice. Hence, the main purpose of this study is to investigate whether curcumin may interfere with macrophage function and polarization after

Indexed as

arginasecurcuminiNOSmalariaphagocytosisRAW 264.7 cells

Identifiers

PMID37896265
PMCPMC10610200
OpenAlexW4387843664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.