Evidence map›Paper›PMID 37896249›Full record

ArticlePharmaceutics2023

Enhancing the Functional Properties of Tea Tree Oil: In Vitro Antimicrobial Activity and Microencapsulation Strategy.

Franco Antonio Manzanelli, Soledad Ravetti, Sofia Gisella Brignone, Ariel Gustavo Garro, Sol Romina Martínez, Mariana Guadalupe Vallejo, Santiago Daniel Palma

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Nano-Enabled Advances in Tea Tree Essential Oil (Materials (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Franco Antonio ManzanelliCentro de Investigaciones y Transferencia de Villa María (CIT VM), Villa María 5900, Argentina.
Soledad RavettiCentro de Investigaciones y Transferencia de Villa María (CIT VM), Villa María 5900, Argentina.ORCID 0000-0003-0236-8530
Sofia Gisella BrignoneUnidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), CONICET, Córdoba 5000, Argentina.
Ariel Gustavo GarroInstituto Académico Pedagógico de Ciencias Humanas, Universidad Nacional de Villa María, Villa María 5900, Argentina.
Sol Romina MartínezInstituto de Investigación en Tecnologías Energéticas y Materiales Avanzados (IITEMA), CONICET, Departamento de Química, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Río Cuarto 5804, Argentina.ORCID 0000-0002-0612-3605
Mariana Guadalupe VallejoUnidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), CONICET, Córdoba 5000, Argentina.
Santiago Daniel PalmaUnidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), CONICET, Córdoba 5000, Argentina.ORCID 0000-0003-2767-9087
Consejo Nacional de Investigaciones Científicas y Técnicas · ARNational University of Villa María · AR

Funding

Financial support from Universidad Nacional de Villa María Res. 2022.358, Res. 2021.384, Res. 2021.111 and Res. 2021.156
6 · The paper itself

Abstract

In the context of addressing antimicrobial drug resistance in periocular infections, Tea Tree Oil (TTO) has emerged as a promising therapeutic option. This study aimed to assess the efficacy of TTO against bacterial strains isolated from ocular infections, with a particular focus on its ability to inhibit biofilm formation. Additionally, we designed and analyzed microcapsules containing TTO to overcome certain unfavorable physicochemical properties and enhance its inherent biological attributes. The quality of TTO was confirmed through rigorous analysis using GC-MS and UV-Vis techniques. Our agar diffusion assay demonstrated the effectiveness of Tea Tree Oil (TTO) against ocular bacterial strains, including

Indexed as

antimicrobial resistancebiological activityessential oilmicrocapsulesperiocular infections

Identifiers

PMID37896249
PMCPMC10610334
OpenAlexW4387775960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.