Evidence map›Paper›PMID 37896192›Full record

ArticlePharmaceutics2023

Nanocrystalline Cellulose as a Versatile Engineering Material for Extrusion-Based Bioprinting.

Sophia A Read, Chee Shuen Go, Miguel J S Ferreira, Cosimo Ligorio, Susan J Kimber, Ahu G Dumanli, Marco A N Domingos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sophia A ReadDepartment of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering & Henry Royce Institute, The University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0003-4260-4059
Chee Shuen GoDepartment of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering & Henry Royce Institute, The University of Manchester, Manchester M13 9PL, UK.
Miguel J S FerreiraDepartment of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering & Henry Royce Institute, The University of Manchester, Manchester M13 9PL, UK.
Cosimo LigorioDepartment of Materials, School of Natural Sciences, Faculty of Science and Engineering & Henry Royce Institute, The University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0001-5917-4652
Susan J KimberDivision of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.ORCID 0000-0002-0568-6342
Ahu G DumanliDepartment of Materials, School of Natural Sciences, Faculty of Science and Engineering & Henry Royce Institute, The University of Manchester, Manchester M13 9PL, UK.
Marco A N DomingosDepartment of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering & Henry Royce Institute, The University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-6693-790X

Funding

Versus Arthritis 20786
6 · The paper itself

Abstract

Naturally derived polysaccharide-based hydrogels, such as alginate, are frequently used in the design of bioinks for 3D bioprinting. Traditionally, the formulation of such bioinks requires the use of pre-reticulated materials with low viscosities, which favour cell viability but can negatively influence the resolution and shape fidelity of the printed constructs. In this work, we propose the use of cellulose nanocrystals (CNCs) as a rheological modifier to improve the printability of alginate-based bioinks whilst ensuring a high viability of encapsulated cells. Through rheological analysis, we demonstrate that the addition of CNCs (1% and 2% (

Indexed as

3D bioprintingalginatebioinksbiomaterialscellulose nanocrystalstissue engineering

Identifiers

PMID37896192
PMCPMC10609932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.