Evidence map›Paper›PMID 37896145›Full record

ArticlePharmaceutics2023

Flexible Fabrication and Hybridization of Bioactive Hydrogels with Robust Osteogenic Potency.

Liang Zhu, Qian Hou, Meijun Yan, Wentao Gao, Guoke Tang, Zhiqing Liu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Liang ZhuDepartment of Orthopedics, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 412001, China.
Qian HouDepartment of Nutrition, Xiangya Hospital, Central South University, Changsha 410008, China.
Meijun YanDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai 200080, China.
Wentao GaoDepartment of Orthopedics, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 412001, China.
Guoke TangDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai 200080, China.
Zhiqing LiuDepartment of Orthopedics, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 412001, China.
Central South University · CNShanghai First People's Hospital · CNXiangya Hospital Central South University · CN

Funding

Interdisciplinary Program of Shanghai Jiao Tong University YG2021ZD34Natural Science Foundation of Hunan Province 2020JJ6017 and 2021JJ31064
6 · The paper itself

Abstract

Osteogenic scaffolds reproducing the natural bone composition, structures, and properties have represented the possible frontier of artificially orthopedic implants with the great potential to revolutionize surgical strategies against the bone-related diseases. However, it is difficult to achieve an all-in-one formula with the simultaneous requirement of favorable biocompatibility, flexible adhesion, high mechanical strength, and osteogenic effects. Here in this work, an osteogenic hydrogel scaffold fabricated by inorganic-in-organic integration between amine-modified bioactive glass (ABG) nanoparticles and poly(ethylene glycol) succinimidyl glutarate-polyethyleneimine (TSG-PEI) network was introduced as an all-in-one tool to flexibly adhere onto the defective tissue and subsequently accelerate the bone formation. Since the N-hydroxysuccinimide (NHS)-ester of tetra-PEG-SG polymer could quickly react with the NH

Indexed as

adhesivebioactive glassbioactive hydrogelsosteogenesistetra-PEG

Identifiers

PMID37896145
PMCPMC10610325
OpenAlexW4387055260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.