Evidence map›Paper›PMID 37895954›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring.

Giorgia Andreozzi, Maria Rosaria Ambrosio, Elisa Magli, Giovanni Maneli, Beatrice Severino, Angela Corvino, Rosa Sparaco, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada and 5 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Giorgia AndreozziDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.
Maria Rosaria AmbrosioURT "Genomic of Diabetes", Institute for Experimental Endocrinology and Oncology "G. Salvatore", National Research Council (IEOS-CNR), Via Pansini 5, 80131 Naples, Italy.
Elisa MagliDipartimento di Sanità Pubblica, Università di Napoli Federico II, Via Pansini, 5, 80131, Naples, Italy.
Giovanni ManeliDepartment of Translational Medicine, University of Naples "Federico II", Via Pansini 5, 80131 Naples, Italy.
Beatrice SeverinoDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.ORCID 0000-0002-3887-8869
Angela CorvinoDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.ORCID 0000-0002-0617-156X
Rosa SparacoDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.
Elisa PerissuttiDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.ORCID 0000-0002-1754-1191
Francesco FrecenteseDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.ORCID 0000-0001-8821-2937
Vincenzo SantagadaDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.
Anna LeśniakDepartment of Pharmacotherapy and Pharmaceutical Care, Centre for Preclinical Research and Technology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.ORCID 0000-0002-6014-9208
Magdalena Bujalska-ZadrożnyDepartment of Pharmacotherapy and Pharmaceutical Care, Centre for Preclinical Research and Technology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.
Giuseppe CaliendoDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.
Pietro FormisanoURT "Genomic of Diabetes", Institute for Experimental Endocrinology and Oncology "G. Salvatore", National Research Council (IEOS-CNR), Via Pansini 5, 80131 Naples, Italy.
Ferdinando FiorinoDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano, 49, 80131 Naples, Italy.ORCID 0000-0001-7357-5751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arylpiperazines represent one of the most important classes of 5-HT

Indexed as

5-HT1A ligandsarylpiperazinesbinding assays, in vitro assay, cytotoxic activity

Identifiers

PMID37895954
PMCPMC10609883

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.