Evidence map›Paper›PMID 37895905›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Yu Liu, Qian Zhang, Yuwei Zhang, Jingnan Wang, Yitian Wu, Guangjie Yang, Jiyun Shi, Fan Wang, Zuojun Xu, Hongli Jing

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06753513 (Clinical Application of 99mTc-FDPH46 SPECT/CT Imaging in Malignant Solid Tumor), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06753513 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Application of 99mTc-FDPH46 SPECT/CT Imaging in Malignant Solid Tumor: a Prospective Exploratory Study

TypeobservationalSponsorZhejiang UniversityRan2024 to 2026Enrolled20ConditionsMalignant Tumors, Solid Tumor MalignancyArms99mTc-FDPH46 SPECT/CT Imaging
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Correlation of FAPI PET Uptake with Immunohistochemistry in Explanted Lungs from Patients with Advanced Interstitial Lung Disease.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Trial
  3. BMJ open · 2026
    Article
  4. Review
  5. Article
  6. FAPI TracerPharmaceuticals (Basel, Switzerland) · 2025
    Article
  7. EJNMMI research · 2025
    Article
  8. Article
  9. Review
  10. The value of fibrosis score andJournal of thoracic disease · 2025
    Article
  11. Collagen Hybridizing Peptide-Based Radiotracers for Molecular Imaging of Collagen Turnover in Pulmonary Fibrosis.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  12. Article
  13. EJNMMI radiopharmacy and chemistry · 2024
    Review
  14. Frontiers in medicine · 2024
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yu LiuDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China.
Qian ZhangDepartment of Respiratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Yuwei ZhangDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China.
Jingnan WangDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China.
Yitian WuDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China.
Guangjie YangDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China.
Jiyun ShiMedical Isotopes Research Center and Department of Radiation Medicine, Scchool of Basic Medical Sciences, Peking University, Beijing 100191, China.ORCID 0000-0001-7220-9637
Fan WangMedical Isotopes Research Center and Department of Radiation Medicine, Scchool of Basic Medical Sciences, Peking University, Beijing 100191, China.ORCID 0000-0002-4166-5776
Zuojun XuDepartment of Respiratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Hongli JingDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University · CN

Funding

National High Level Hospital Clinical Research Funding 2022-PUMCH-B-071
6 · The paper itself

Abstract

aimIdiopathic pulmonary fibrosis (IPF) is associated with a poor prognosis, presenting the most aggressive form of interstitial lung diseases (ILDs). Activated fibroblasts are crucial for pathological processes. Fibroblast activation protein (FAP) inhibitor (FAPI) tracers would be promising imaging agents for these diseases. The purpose of this study was to evaluate a

methodsEleven IPF patients (nine males and two females; age range 55-75 year) were included in this pilot study.

resultsNormal physiological uptake of

conclusionsOur preliminary data show that the

Indexed as

99mTc-HFAPIdosimetryidiopathic pulmonary fibrosis (IPF)SPECT

Identifiers

PMID37895905
PMCPMC10610005
OpenAlexW4387452258

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.