Evidence map›Paper›PMID 37895643›Full record

ReviewMaterials (Basel, Switzerland)2023

4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications.

Irene Chiesa, Maria Rachele Ceccarini, Silvia Bittolo Bon, Michela Codini, Tommaso Beccari, Luca Valentini, Carmelo De Maria

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. 3D printable tough hydrogel actuators.Materials horizons · 2026
    Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Irene ChiesaDepartment of Ingegneria dell'Informazione and Research Center E. Piaggio, University of Pisa, Largo Lucio Lazzarino 1, 56122 Pisa, Italy.ORCID 0000-0002-1260-4990
Maria Rachele CeccariniDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-5344-4890
Silvia Bittolo BonPhysics and Geology Department, University of Perugia, Via Pascoli, 06123 Perugia, Italy.ORCID 0000-0002-1546-5826
Michela CodiniDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-1562-4495
Tommaso BeccariDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0001-9637-6579
Luca ValentiniCivil and Environmental Engineering Department, University of Perugia, Strada di Pentima 4, 05100 Terni, Italy.ORCID 0000-0002-6803-5889
Carmelo De MariaDepartment of Ingegneria dell'Informazione and Research Center E. Piaggio, University of Pisa, Largo Lucio Lazzarino 1, 56122 Pisa, Italy.ORCID 0000-0002-1368-3571

Funding

Ministry of Education, Universities and Research National Innovation Ecosystem grant ECS00000041_VITALITYMinistry of Education, Universities and Research PRIN 2017FWC3WC
6 · The paper itself

Abstract

Four-dimensional (4D) printing is an innovative additive manufacturing technology used to fabricate structures that can evolve over time when exposed to a predefined environmental stimulus. 4D printed objects are no longer static objects but programmable active structures that accomplish their functions thanks to a change over time in their physical/chemical properties that usually displays macroscopically as a shapeshifting in response to an external stimulus. 4D printing is characterized by several entangled features (e.g., involved material(s), structure geometry, and applied stimulus entities) that need to be carefully coupled to obtain a favorable fabrication and a functioning structure. Overall, the integration of micro-/nanofabrication methods of biomaterials with nanomaterials represents a promising approach for the development of advanced materials. The ability to construct complex and multifunctional triggerable structures capable of being activated allows for the control of biomedical device activity, reducing the need for invasive interventions. Such advancements provide new tools to biomedical engineers and clinicians to design dynamically actuated implantable devices. In this context, the aim of this review is to demonstrate the potential of 4D printing as an enabling manufacturing technology to code the environmentally triggered physical evolution of structures and devices of biomedical interest.

Indexed as

4D printingbioengineeringbiomaterialsfunctional materials

Identifiers

PMID37895643
PMCPMC10608699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.