Evidence map›Paper›PMID 37895313›Full record

ArticleGenes2023

Notch Signaling Regulates Mouse Perivascular Adipose Tissue Function via Mitochondrial Pathways.

Chenhao Yang, Xuehui Yang, Anne Harrington, Christian Potts, Abigail Kaija, Larisa Ryzhova, Lucy Liaw

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. NOTCH Signaling Networks in Perivascular Adipose Tissue.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  5. The Role of N6-Methyladenosine in Mitochondrial Dysfunction and Pathology.International journal of molecular sciences · 2025
    Review
  6. NCardiovascular diabetology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chenhao YangCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME 04074, USA.ORCID 0000-0002-7495-5163
Xuehui YangCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME 04074, USA.
Anne HarringtonCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME 04074, USA.
Christian PottsCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME 04074, USA.
Abigail KaijaCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME 04074, USA.
Larisa RyzhovaCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME 04074, USA.
Lucy LiawCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME 04074, USA.
MaineHealth · US

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI Kimberly Luebbers · 2017 to 2026
$51.6M
The role of night shift work in metabolic disorders during and after pregnancyP20GM121301 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN · 2017 to 2026
$25.1M
Regulation of arterial phenotype by perivascular adipose tissue in cardiometabolic diseaseR01HL141149 · NHLBI · MAINEHEALTH · PI LIAW, LUCY · 2018 to 2025
$4.3M
NHLBI NIH HHS R01 HL141149NIGMS NIH HHS P20 GM121301NIGMS NIH HHS U54 GM115516
6 · The paper itself

Abstract

Perivascular adipose tissue (PVAT) regulates vascular function by secreting vasoactive substances. In mice, Notch signaling is activated in the PVAT during diet-induced obesity, and leads to the loss of the thermogenic phenotype and adipocyte whitening due to increased lipid accumulation. We used the Adiponectin-Cre (

Indexed as

Adipose TissueProteomicsAdiponectinAnimalsMiceMitochondriaObesitySignal TransductionAdiponectinmitochondrial dynamicsNotch signalingperivascular adipose tissue

Identifiers

PMID37895313
PMCPMC10606454
OpenAlexW4387821680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.