Evidence map›Paper›PMID 37895094›Full record

ArticleInternational journal of molecular sciences2023

Synthesis, Cytotoxic Activity and In Silico Study of Novel Dihydropyridine Carboxylic Acids Derivatives.

Ricardo Ballinas-Indilí, María Inés Nicolás-Vázquez, Joel Martínez, María Teresa Ramírez-Apan, Cecilio Álvarez-Toledano, Alfredo Toscano, Maricarmen Hernández-Rodríguez, Elvia Mera Jiménez, René Miranda Ruvalcaba

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ricardo Ballinas-IndilíDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Avenida 1o de Mayo s/n, Colonia Santa María las Torres, Cuautitlán Izcalli 54740, Mexico.
María Inés Nicolás-VázquezDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Avenida 1o de Mayo s/n, Colonia Santa María las Torres, Cuautitlán Izcalli 54740, Mexico.ORCID 0000-0003-0722-5045
Joel MartínezDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Avenida 1o de Mayo s/n, Colonia Santa María las Torres, Cuautitlán Izcalli 54740, Mexico.ORCID 0000-0002-6683-6738
María Teresa Ramírez-ApanInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, Mexico City 04510, Mexico.
Cecilio Álvarez-ToledanoInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, Mexico City 04510, Mexico.ORCID 0000-0002-1983-2937
Alfredo ToscanoInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, Mexico City 04510, Mexico.ORCID 0000-0002-4380-9251
Maricarmen Hernández-RodríguezLaboratorio de Cultivo Celular, Sección de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0001-9371-1095
Elvia Mera JiménezLaboratorio de Cultivo Celular, Sección de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
René Miranda RuvalcabaDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Avenida 1o de Mayo s/n, Colonia Santa María las Torres, Cuautitlán Izcalli 54740, Mexico.ORCID 0000-0002-1979-5590
Universidad de Cuautitlán Izcalli · MXUniversidad Nacional Autónoma de México · MXInstituto Politécnico Nacional · MX

Funding

Universidad Nacional Autónoma de México PAPIIT IN212421 and IN213523
6 · The paper itself

Abstract

To aid the possible prevention of multidrug resistance in tumors and cause lower toxicity, a set of sixteen novel dihydropyridine carboxylic acids derivatives

Indexed as

Antineoplastic AgentsDihydropyridinesNeoplasmsCarboxylic AcidsCell LineHumansMolecular Docking SimulationMolecular StructureOrganic ChemicalsStructure-Activity RelationshipAntineoplastic AgentsCarboxylic AcidsDihydropyridinesOrganic Chemicalscytotoxic activitydihydropyridine carboxylic acidin silico DFTynones

Identifiers

PMID37895094
PMCPMC10607468
OpenAlexW4387843845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.