Evidence map›Paper›PMID 37895087›Full record

ArticleInternational journal of molecular sciences2023

Pomegranate Peel Extract Differently Modulates Gene Expression in Gingiva-Derived Mesenchymal Stromal Cells under Physiological and Inflammatory Conditions.

Miodrag Čolić, Nataša Miljuš, Jelena Đokić, Marina Bekić, Aleksandra Krivokuća, Sergej Tomić, Dušan Radojević, Marina Radanović, Mile Eraković, Bashkim Ismaili and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Miodrag ČolićSerbian Academy of Sciences and Arts, 11000 Belgrade, Serbia.
Nataša MiljušFaculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina.ORCID 0000-0003-0299-7716
Jelena ĐokićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.
Marina BekićInstitute for the Application of Nuclear Energy, University of Belgrade, 11080 Belgrade, Serbia.
Aleksandra KrivokućaFaculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina.
Sergej TomićInstitute for the Application of Nuclear Energy, University of Belgrade, 11080 Belgrade, Serbia.ORCID 0000-0003-2570-1295
Dušan RadojevićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.
Marina RadanovićMedical Faculty Foča, University of East Sarajevo, 73300 Foča, Bosnia and Herzegovina.
Mile ErakovićClinic for Stomatology, Medical Faculty of the Military Medical Academy, University of Defense, 11154 Belgrade, Serbia.
Bashkim IsmailiFaculty of Dental Medicine, International Balkan University, 1000 Skopje, North Macedonia.
Ranko ŠkrbićFaculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina.ORCID 0000-0002-6643-1781
University of Belgrade · RSUniversity of Banja Luka · BAInternational Balkan University · MKMilitary Medical Academy · RSSerbian Academy of Sciences and Arts · RSUniversity of East Sarajevo · BA

Funding

Medical Faculty Banja Luka, University of Banja Luka, Bosnia and Herzegovina N/AMinistry of Education, Science and Technological Development, Republic of Serbia 451-03-68/2020-14/200019University of Defense in Belgrade, Medical Faculty of the Military Medical Academy, Belgrade, Serbia MFVMA/03/20-22University of East Sarajevo, Medical Faculty Foča, Foča, Bosnia and Herzegovina UIS/MFF: I.1.20-22
6 · The paper itself

Abstract

Pomegranate has shown a favorable effect on gingivitis/periodontitis, but the mechanisms involved are poorly understood. The aim of this study was to test the effect of pomegranate peel extract (PoPEx) on gingiva-derived mesenchymal stromal cells (GMSCs) under physiological and inflammatory conditions. GMSC lines from healthy (H) and periodontitis (P) gingiva (

Indexed as

Mesenchymal Stem CellsPeriodontitisPomegranateCell DifferentiationChemokine CXCL10Gene ExpressionGingivaHumansInterleukin-6LipopolysaccharidesMatrix Metalloproteinase 3Toll-Like Receptor 3Transforming Growth Factor betaChemokine CXCL10Interleukin-6LipopolysaccharidesMatrix Metalloproteinase 3Toll-Like Receptor 3Transforming Growth Factor betagene expressiongingivamesenchymal stromal cellsperiodontitispomegranate

Identifiers

PMID37895087
PMCPMC10607867
OpenAlexW4387843727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.