Cranial Neural Crest Specific Deletion of

Naoto Ohkura, Hwa Kyung Nam, Fei Liu, Nan Hatch

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

0.4field-weighted citation impact, top 32% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
Article
JBMR plus · 2026
Article
Dentoalveolar defects and impaired alveolar bone healing in a neural crest directed conditional knockout mouse model of hypophosphatasia.Bone · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Naoto OhkuraDepartment of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-3807-2328

Hwa Kyung NamDepartment of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.

Fei LiuDepartment of Biomaterials Sciences and Prosthodontics, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.

Nan HatchDepartment of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-2632-0841

University of Michigan · US

Funding

Molecular Mechanisms of CraniosynostosisR01DE025827 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HATCH, NAN E · 2016 to 2020

$2.0M

NIDCR NIH HHS R01 DE025827

6 · The paper itself

Abstract

Bone growth plate abnormalities and skull shape defects are seen in hypophosphatasia, a heritable disorder in humans that occurs due to the deficiency of tissue nonspecific alkaline phosphatase (TNAP,

Indexed as

Alkaline PhosphataseChondrocytesAnimalsCell DifferentiationIntegrasesMiceNeural CrestParathyroid Hormone-Related ProteinSkull BaseAlkaline PhosphataseALPL protein, mouseCre recombinaseIntegrasesParathyroid Hormone-Related Proteinchondrocytecranial basecranial neural cresthypophosphatasiaphosphatepyrophosphatesynchondrosistissue nonspecific alkaline phosphatase

Identifiers

PMID37895082

DOI10.3390/ijms242015401

PMCPMC10607232

OpenAlexW4387823028

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.