Evidence map›Paper›PMID 37894940›Full record

ArticleInternational journal of molecular sciences2023

Single-Nucleotide Polymorphism in Genes Encoding G Protein Subunits

Simon Birkner, Birte Möhlendick, Benjamin Wilde, Kristina Schoenfelder, Kristina Boss, Winfried Siffert, Andreas Kribben, Justa Friebus-Kardash

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. TheJournal of the American Heart Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Simon BirknerDepartment of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Birte MöhlendickInstitute of Pharmacogenetics, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0001-9093-8585
Benjamin WildeDepartment of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Kristina SchoenfelderDepartment of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Kristina BossDepartment of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Winfried SiffertInstitute of Pharmacogenetics, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Andreas KribbenDepartment of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Justa Friebus-KardashDepartment of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.ORCID 0000-0002-6747-1240
Essen University Hospital · DEUniversity of Duisburg-Essen · DE

Funding

Clinician Scientist Program of the University Medicine Essen Clinician Scientist Academy (UMEA) no number
6 · The paper itself

Abstract

Single-nucleotide polymorphisms in G protein subunits are linked to an increased risk of cardiovascular events among the general population. We assessed the effects of

Indexed as

Coronary StenosisHeterotrimeric GTP-Binding ProteinsFemaleGenotypeGTP-Binding Protein alpha Subunits, Gq-G11HumansMalePolymorphism, Single NucleotideProtein SubunitsRenal DialysisRenal Replacement TherapyGNAQ protein, humanGTP-Binding Protein alpha Subunits, Gq-G11Heterotrimeric GTP-Binding ProteinsProtein Subunitscardiovascular eventscoronary artery stent insertionGNAQ −695/−694GC > TTGNAS c.393C > TGNB3 c.825C > Tleft ventricular end-diastolic diameter (LVEDD)renal replacement therapy (RRT)

Identifiers

PMID37894940
PMCPMC10607787
OpenAlexW4387702885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.