Proximal Tubular

Chi Zhang, Zhihuang Zheng, Kexin Xu, Guozhe Cheng, Huijuan Wu, Jun Liu

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.4field-weighted citation impact, top 35% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

Metabolic memory in the kidney: how lactate and lactylation drive the path from acute injury to chronic disease.Renal failure · 2026
Review
The HDAC1 inhibitor attenuates renal ischemia-reperfusion injury via dual epigenetic modulation of p53 and macrophage NF-κB pathways.Cell biology and toxicology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chi ZhangDepartment of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201600, China.

Zhihuang ZhengDepartment of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201600, China.

Kexin XuDepartment of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201600, China.

Guozhe ChengDepartment of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201600, China.

Huijuan WuDepartment of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai 200030, China.ORCID 0000-0003-4681-4440

Jun LiuDepartment of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201600, China.ORCID 0000-0003-4584-8200

Shanghai First People's Hospital · CNShanghai Medical College of Fudan University · CN

Funding

National Natural Science Foundation of China 82070718Technology Innovation Natural Foundation 20ZR1444700

6 · The paper itself

Abstract

The Hippo pathway mediates renal maladaptive repair after acute kidney injury (AKI), which has been considered a driving force in the progression to chronic kidney disease (CKD). LATS2, a core kinase of the Hippo pathway, exerts non-Hippo-dependent functions in the regulation of the cell cycle and cell fate, providing new insights into AKI and further repair. However, its role remains unknown. Here, we utilized a proximal tubular

Indexed as

Acute Kidney InjuryRenal Insufficiency, ChronicReperfusion InjuryAnimalsApoptosisbcl-2-Associated X ProteinKidneyMiceMice, Inbred C57BLProtein Serine-Threonine KinasesTumor Suppressor Protein p53Up-Regulationbcl-2-Associated X ProteinLats1 protein, mouseProtein Serine-Threonine KinasesTrp53 protein, mouseTumor Suppressor Protein p53acute kidney injuryapoptosisLATS2maladaptive repairp53

Identifiers

PMID37894939

DOI10.3390/ijms242015258

PMCPMC10607662

OpenAlexW4387702794

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.