Evidence map›Paper›PMID 37894936›Full record

ArticleInternational journal of molecular sciences2023

Adipocytes in the Uterine Wall during Experimental Healing and in Cesarean Scars during Pregnancy.

Natalia Tikhonova, Andrey P Milovanov, Valentina V Aleksankina, Ilyas A Kulikov, Tatiana V Fokina, Andrey P Aleksankin, Tamara N Belousova, Ludmila M Mikhaleva, Natalya V Niziaeva

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Serum Markers of Abnormal Placental Attachment in Pregnant Women.Bulletin of experimental biology and medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Natalia TikhonovaAvtsyn Research Institute of Human Morphology of FSBSI "Petrovsky National Research Centre of Surgery", 119991 Moscow, Russia.ORCID 0000-0001-5437-6933
Andrey P MilovanovAvtsyn Research Institute of Human Morphology of FSBSI "Petrovsky National Research Centre of Surgery", 119991 Moscow, Russia.
Valentina V AleksankinaAvtsyn Research Institute of Human Morphology of FSBSI "Petrovsky National Research Centre of Surgery", 119991 Moscow, Russia.
Ilyas A KulikovSBHI of the Moscow Region "Vidnovsky Perinatal Center", 142700 Moscow, Russia.
Tatiana V FokinaAvtsyn Research Institute of Human Morphology of FSBSI "Petrovsky National Research Centre of Surgery", 119991 Moscow, Russia.
Andrey P AleksankinAvtsyn Research Institute of Human Morphology of FSBSI "Petrovsky National Research Centre of Surgery", 119991 Moscow, Russia.ORCID 0000-0001-6686-0896
Tamara N BelousovaSBHI of the Moscow Region "Vidnovsky Perinatal Center", 142700 Moscow, Russia.
Ludmila M MikhalevaAvtsyn Research Institute of Human Morphology of FSBSI "Petrovsky National Research Centre of Surgery", 119991 Moscow, Russia.ORCID 0000-0003-2052-914X
Natalya V NiziaevaAvtsyn Research Institute of Human Morphology of FSBSI "Petrovsky National Research Centre of Surgery", 119991 Moscow, Russia.ORCID 0000-0001-5592-5690
Research Institute of Human Morphology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have suggested that adipocytes in uterine scars may affect the development of the placenta accrete spectrum (PAS). In the experimental part, we explored adipocytes in the uterine wall by the twelfth sexual cycle after surgery. In the clinical part, we investigated adipocyte clusters in the cesarean scar of pregnant women with and without PAS. The uterine wall was evaluated in gross and histological sections using morphometry, histochemistry (hematoxylin and eosin stain, Mallory stain), and immunohistochemistry for FABP4 (adipocyte markers), CD68, CD163, CD206 (macrophages), CD 34 (endothelium), cytokeratin 8 (epithelium), aSMA (smooth muscle cells). The design included an experimental study on Sprague-Dawley rats (n = 18) after a full-thickness surgical incision on the seventh (n = 6), 30th (n = 6), and 60th day (n = 6). The clinical groups include pregnant women without uterine scars (n = 10), pregnant women with a uterine scar after previous cesarean sections (n = 10), and women with PAS (n = 11). Statistical processing was carried out using nonparametric methods. Comparisons were conducted using the Mann-Whitney U-test and Kruskal-Wallis test. Statistical significance was considered at

Indexed as

CicatrixSurgical WoundAdipocytesAnimalsCesarean SectionFemaleHumansPregnancyRatsRats, Sprague-DawleyUterusadipocytescaesarean sectionmacrophagesplacenta accreta spectrumSprague–Dawleyuterine scaruterine wall healinguterus

Identifiers

PMID37894936
PMCPMC10607476
OpenAlexW4387705679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.