Evidence map›Paper›PMID 37894839›Full record

ArticleInternational journal of molecular sciences2023

Insensitive Effects of Inflammatory Cytokines on the Reference Genes of Synovial Fluid Resident-Mesenchymal Stem Cells Derived from Rheumatoid Arthritis Patients.

Eun-Yeong Bok, Saet-Byul Kim, Gitika Thakur, Yong-Ho Choe, Seong-Ju Oh, Sun-Chul Hwang, Sun-A Ock, Gyu-Jin Rho, Sang-Il Lee, Won-Jae Lee and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Long Non-Coding RNAsCurrent issues in molecular biology · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Eun-Yeong BokCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Saet-Byul KimCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Gitika ThakurCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0001-7245-6048
Yong-Ho ChoeCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Seong-Ju OhCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0003-3849-0300
Sun-Chul HwangDepartment of Orthopaedic Surgery, Gyeongsang National University, School of Medicine and Hospital, Jinju 52727, Republic of Korea.
Sun-A OckAnimal Biotechnology Division, National Institute of Animal Science (NIAS), Rural Development Administration (RDA), 1500, Kongjwipatjwi-ro, Isero-myeon, Wanju-gun 565851, Republic of Korea.
Gyu-Jin RhoCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Sang-Il LeeDepartment of Internal Medicine and Institute of Health Sciences, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Republic of Korea.
Won-Jae LeeCollege of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0003-1462-7798
Sung-Lim LeeCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0002-1055-8097
Gyeongsang National University · KRGyeongsang National University Hospital · KRRural Development Administration · KR

Funding

National Research Foundation of Korea NRF-2021R1A2C1007054
6 · The paper itself

Abstract

Mesenchymal stem cells derived from rheumatoid arthritis patients (RA-MSCs) provide an understanding of a variety of cellular and immunological responses within the inflammatory milieu. Sustained exposure of MSCs to inflammatory cytokines is likely to exert an influence on genetic variations, including reference genes (RGs). The sensitive effect of cytokines on the reference genes of RA-SF-MSCs may be a variation factor affecting patient-derived MSCs as well as the accuracy and reliability of data. Here, we comparatively evaluated the stability levels of nine RG candidates, namely

Indexed as

Arthritis, RheumatoidMesenchymal Stem CellsCytokinesGene Expression ProfilingHumansReal-Time Polymerase Chain ReactionReference StandardsReproducibility of ResultsSynovial FluidTumor Necrosis Factor-alphaCytokinesTumor Necrosis Factor-alphainflammatory cytokinespatient-derived mesenchymal stem cellquantitative polymerase chain reactionreference generheumatoid arthritis

Identifiers

PMID37894839
PMCPMC10607131
OpenAlexW4387614923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.