Evidence map›Paper›PMID 37894811›Full record

ArticleInternational journal of molecular sciences2023

Thrombin-Induced COX-2 Expression and PGE

Chien-Chung Yang, I-Ta Lee, Yan-Jyun Lin, Wen-Bin Wu, Li-Der Hsiao, Chuen-Mao Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chien-Chung YangDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital at Taoyuan, Taoyuan 333008, Taiwan.ORCID 0000-0003-2325-5017
I-Ta LeeSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0002-8451-0280
Yan-Jyun LinPh.D. Program for Biotech Pharmaceutical Industry, China Medical University, Taichung 406040, Taiwan.
Wen-Bin WuSchool of Medicine, Fu Jen Catholic University, New Taipei City 242062, Taiwan.ORCID 0000-0001-9248-5030
Li-Der HsiaoGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242062, Taiwan.
Chuen-Mao YangGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242062, Taiwan.ORCID 0000-0002-3208-5438
Fu Jen Catholic University · TWChina Medical University · TW

Funding

Chang Gung Medical Research Foundation, Taiwan CMRPG5L0181China Medical University, Taiwan CMU111-MF-05National Science and Technology Council, Taiwan MOST110-2320-B-039-071National Science and Technology Council, Taiwan MOST111-2320-B-039-014
6 · The paper itself

Abstract

In this study, we confirmed that thrombin significantly increases the production of COX-2 and PGE

Indexed as

Proto-Oncogene Proteins c-aktTranscription Factor AP-1CSK Tyrosine-Protein KinaseCyclooxygenase 2DinoprostoneErbB ReceptorsFocal Adhesion Kinase 1Focal Adhesion Kinase 2HumansInflammationMyocytes, Smooth MusclePhosphatidylinositol 3-KinasesProtein Kinase C-deltaResveratrolsrc-Family KinasesThrombinCSK Tyrosine-Protein KinaseCyclooxygenase 2DinoprostoneErbB ReceptorsFocal Adhesion Kinase 1Focal Adhesion Kinase 2Phosphatidylinositol 3-KinasesPRKCD protein, humanProtein Kinase C-deltaProto-Oncogene Proteins c-aktPTGS2 protein, humanPTK2 protein, humanResveratrolsrc-Family KinasesThrombinTranscription Factor AP-1airway inflammationcyclooxygenasehuman tracheal smooth muscle cellprostaglandin E2resveratrolthrombin

Identifiers

PMID37894811
PMCPMC10606820
OpenAlexW4387607256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.