Evidence map›Paper›PMID 37894755›Full record

ArticleInternational journal of molecular sciences2023

Synthesis and Characterization of a Biopolymer Pectin/Ethanolic Extract from Olive Mill Wastewater: In Vitro Safety and Efficacy Tests on Skin Wound Healing.

Francesca Aiello, Rocco Malivindi, Marisa Francesca Motta, Pasquale Crupi, Rosa Nicoletti, Cinzia Benincasa, Maria Lisa Clodoveo, Vittoria Rago, Umile Gianfranco Spizzirri, Donatella Restuccia

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Phytochemical Analysis and Biological Activities ofPlants (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Francesca AielloDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0001-6846-5582
Rocco MalivindiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-8313-2492
Marisa Francesca MottaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.
Pasquale CrupiInterdisciplinary Department of Medicine, University Aldo Moro Bari, 70121 Bari, Italy.ORCID 0000-0001-6457-8619
Rosa NicolettiCouncil for Agricultural Research and Economics (CREA), Research Centre for Olive, Fruit and Citrus Crops, Via Settimio Severo 83, 87036 Rende, Italy.ORCID 0000-0001-9588-9591
Cinzia BenincasaCouncil for Agricultural Research and Economics (CREA), Research Centre for Olive, Fruit and Citrus Crops, Via Settimio Severo 83, 87036 Rende, Italy.ORCID 0000-0002-2590-2866
Maria Lisa ClodoveoInterdisciplinary Department of Medicine, University Aldo Moro Bari, 70121 Bari, Italy.ORCID 0000-0002-1717-2197
Vittoria RagoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0003-3971-7378
Umile Gianfranco SpizzirriDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-5447-9497
Donatella RestucciaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-3415-3828
University of Calabria · ITUniversity of Bari Aldo Moro · ITUniversity of Basilicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound-healing delay is one of the major problems of type 2 diabetes, representing also a clinical emergency in non-healing chronic wounds. Natural antioxidants show interesting wound-healing properties, including those extracted from waste derived from olive oil production. Olive mill wastewater is one of the main by-products of the olive oil-making process, and it is rich in high-value secondary metabolites, mainly hydroxytyrosol. We proposed an eco-friendly extraction method, employing both ultrasound-assisted and Soxhlet techniques and ethanol as a solvent, to recover valuable molecules from Roggianella cv (

Indexed as

Diabetes Mellitus, Type 2OleaAnimalsAntioxidantsOlive OilPectinsSwineWastewaterAntioxidantsOlive OilPectinsWastewaterantioxidant moleculesolive mill wastewaterultra-sound-assisted extractionwound healing

Identifiers

PMID37894755
PMCPMC10606433
OpenAlexW4387539563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.