Evidence map›Paper›PMID 37894695›Full record

ArticleMolecules (Basel, Switzerland)2023

In Vivo Trafficking of the Anticancer Drug Tris(8-Quinolinolato) Gallium (III) (KP46) by Gallium-68/67 PET/SPECT Imaging.

Afnan M F Darwesh, Cinzia Imberti, Joanna J Bartnicka, Fahad Al-Salemee, Julia E Blower, Alex Rigby, Jayanta Bordoloi, Alex Griffiths, Michelle T Ma, Philip J Blower

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Transmetalation in Cancer Pharmacology.International journal of molecular sciences · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Afnan M F DarweshCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.ORCID 0000-0002-5191-1520
Cinzia ImbertiCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.ORCID 0000-0003-1187-7951
Joanna J BartnickaCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.
Fahad Al-SalemeeCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.
Julia E BlowerCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.
Alex RigbyCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.ORCID 0000-0003-2221-1602
Jayanta BordoloiCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.
Alex GriffithsLondon Metallomics Facility, King's College London, London SE1 9NH, UK.
Michelle T MaCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.
Philip J BlowerCollege London, School of Biomedical Engineering and Imaging Sciences, St. Thomas' Hospital, London SE1 7EH, UK.ORCID 0000-0001-6290-1590
St Thomas' Hospital · GBLondon Metropolitan University · GB

Funding

Wellcome TrustWellcome Trust 202902/Z/16/ZWellcome Trust 203148/Z/16/ZWellcome Trust 212885/Z/18/Z
6 · The paper itself

Abstract

KP46 (tris(hydroxyquinolinato)gallium(III)) is an experimental, orally administered anticancer drug. Its absorption, delivery to tumours, and mode of action are poorly understood. We aimed to gain insight into these issues using gallium-67 and gallium-68 as radiotracers with SPECT and PET imaging in mice. [

Indexed as

Antineoplastic AgentsGalliumNeoplasmsOrganometallic CompoundsAcetatesAnimalsGallium RadioisotopesHumansMicePositron-Emission TomographyTomography, Emission-Computed, Single-PhotonAcetatesAntineoplastic AgentsGalliumGallium-67Gallium-68Gallium RadioisotopesOrganometallic Compounds8-hydroxyquinolinecancergalliumKP46PET imagingradionuclide imagingSPECT imaging

Identifiers

PMID37894695
PMCPMC10609081
OpenAlexW4387860291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.