Evidence map›Paper›PMID 37894669›Full record

ArticleMolecules (Basel, Switzerland)2023

Anti-Neurodegenerating Activity: Structure-Activity Relationship Analysis of Flavonoids.

Gagan Preet, Ahlam Haj Hasan, Piteesha Ramlagan, Shameem Fawdar, Fabien Boulle, Marcel Jaspars

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Gagan PreetMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.ORCID 0000-0002-7978-7306
Ahlam Haj HasanMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.ORCID 0000-0001-9609-4109
Piteesha RamlaganAxonova Ltd., Grand Port 51405, Mauritius.ORCID 0009-0007-5987-8124
Shameem FawdarAxonova Ltd., Grand Port 51405, Mauritius.ORCID 0000-0003-4639-057X
Fabien BoulleAxonova Ltd., Grand Port 51405, Mauritius.
Marcel JasparsMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.ORCID 0000-0002-2426-6028
Visma (Norway) · NOUniversity of Aberdeen · GBJordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An anti-neurodegeneration activity study was carried out for 80 flavonoid compounds. The structure-activity analysis of the structures was carried out by performing three different anti-neurodegeneration screening tests, showing that in these structures, the presence of a hydroxy substituent group at position C3' as well as C5' of ring B and a methoxy substituent group at the C7 position of ring A play a vital role in neuroprotective and antioxidant as well as anti-inflammatory activity. Further, we found structure (

Indexed as

AntioxidantsFlavonoidsMolecular Docking SimulationStructure-Activity RelationshipAntioxidantsFlavonoidscomputationalflavonesflavonoidsin siliconeurodegenerationSAR

Identifiers

PMID37894669
PMCPMC10609304
OpenAlexW4387813424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.