Evidence map›Paper›PMID 37894606›Full record

ArticleMolecules (Basel, Switzerland)2023

Development and Characterization of High-Absorption Microencapsulated Organic Propolis EPP-AF

Andresa A Berretta, Jéssica A De Lima, Soraia I Falcão, Ricardo Calhelha, Nathaly Alcazar Amorim, Isabella Salgado Gonçalves, Luana Gonçalves Zamarrenho, Hernane da Silva Barud, Jairo Kenupp Bastos, David De Jong and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Effects ofLife (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Andresa A BerrettaDepartment of Research, Development & Innovation, Apis Flora Indl. Coml. Ltd.a., Ribeirão Preto 14020-670, Brazil.ORCID 0000-0001-5719-1301
Jéssica A De LimaDepartment of Research, Development & Innovation, Apis Flora Indl. Coml. Ltd.a., Ribeirão Preto 14020-670, Brazil.
Soraia I FalcãoCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-3735-6951
Ricardo CalhelhaCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-6801-4578
Nathaly Alcazar AmorimDepartment of Research, Development & Innovation, Apis Flora Indl. Coml. Ltd.a., Ribeirão Preto 14020-670, Brazil.
Isabella Salgado GonçalvesBiopolymers and Biomaterials Group, University of Araraquara, UNIARA, Araraquara 14801-320, Brazil.
Luana Gonçalves ZamarrenhoDepartment of Research, Development & Innovation, Apis Flora Indl. Coml. Ltd.a., Ribeirão Preto 14020-670, Brazil.
Hernane da Silva BarudBiopolymers and Biomaterials Group, University of Araraquara, UNIARA, Araraquara 14801-320, Brazil.
Jairo Kenupp BastosDepartment of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, Brazil.
David De JongGenetics Department, Ribeirão Preto Medical School, University of São Paulo (FMRP/USP), Ribeirão Preto 14049-900, Brazil.ORCID 0000-0003-2131-9988
Miguel Vilas-BoasCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-8665-5280
Universidade de São Paulo · BRPolytechnic Institute of Bragança · PTApis Flora (Brazil) · BRCentro Universitário de Araraquara · BR

Funding

Fundação para a Ciência e Tecnologia UIDB/00690/2020National Council for Scientific and Technological Development 309614/2021-0National Council for Scientific and Technological Development 350088/2022-5National Council for Scientific and Technological Development 350089/2022-1National Council for Scientific and Technological Development 424727/2021-8São Paulo Research Foundation 2013/07276-1São Paulo Research Foundation 2017/04138-8Southern University of Science and Technology LA/P/0007/2021
6 · The paper itself

Abstract

The demand for organic and functional food continues to increase yearly. Among the available functional foods, propolis is a bee product that has various beneficial properties, including antimicrobial, antioxidant, and anti-inflammatory activities. However, it generally is only available in ethanol solution, which has poor bioavailability, as it is relatively insoluble in water. The use of such ethanol extracts is often objectionable because of the alcohol content and because they have a strong and striking taste. Development of alternatives that can efficiently and safely increase solubility in water, and that meet organic production specifications, has been a challenge. To address these concerns, microcapsules were developed using spray-dryer technology from an emulsion based on EPP-AF

Indexed as

Anti-Infective AgentsPropolisAnti-Inflammatory AgentsAntioxidantsCaco-2 CellsCapsulesEthanolHumansSpectroscopy, Fourier Transform InfraredWaterAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsCapsulesEthanolPropolisWateranti-inflammatoryantimicrobialantioxidantantitumorbioavailabilitymicroencapsulated propolis extractpermeability

Identifiers

PMID37894606
PMCPMC10609166
OpenAlexW4387702671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.