Evidence map›Paper›PMID 37894574›Full record

ReviewMolecules (Basel, Switzerland)2023

A Review of Chondroitin Sulfate's Preparation, Properties, Functions, and Applications.

Qingshan Shen, Yujie Guo, Kangyu Wang, Chunhui Zhang, Yanli Ma

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
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  13. EstablishingBiodesign research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Qingshan ShenZhang Zhongjing College of Chinese Medicine, Nanyang Institute of Technology, Changjiang Road 80, Nanyang 473004, China.
Yujie GuoKey Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Kangyu WangKey Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Chunhui ZhangKey Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Yanli MaZhang Zhongjing College of Chinese Medicine, Nanyang Institute of Technology, Changjiang Road 80, Nanyang 473004, China.
Chinese Academy of Agricultural Sciences · CNInstitute of Agro-Products Processing Science and Technology · CNInstitute of Food Science and Technology · CNMinistry of Agriculture and Rural Affairs · CNNanyang Institute of Technology · CN

Funding

Nanyang City Collaborative Innovation Major Project P. sibiricum Series Functional Food Research and Development Key Technology and Industrial Application Project 21XTCX12005Provincial Natural Science Foundation of Henan 232300420215Technical Breathrough Projects of Inner Mongolia Science and Technology Program 2022JBGS0007The Open Project of Zhang Zhongjing Key Laboratory of Prescription Medicine and Immune Regulation in Henan Province KFKT20221002The Youth Backbone Teacher Training Program of Colleges and Universities of Henan Province 2020GGJS226
6 · The paper itself

Abstract

Chondroitin sulfate (CS) is a natural macromolecule polysaccharide that is extensively distributed in a wide variety of organisms. CS is of great interest to researchers due to its many in vitro and in vivo functions. CS production derives from a diverse number of sources, including but not limited to extraction from various animals or fish, bio-synthesis, and fermentation, and its purity and homogeneity can vary greatly. The structural diversity of CS with respect to sulfation and saccharide content endows this molecule with distinct complexity, allowing for functional modification. These multiple functions contribute to the application of CS in medicines, biomaterials, and functional foods. In this article, we discuss the preparation of CS from different sources, the structure of various forms of CS, and its binding to other relevant molecules. Moreover, for the creation of this article, the functions and applications of CS were reviewed, with an emphasis on drug discovery, hydrogel formation, delivery systems, and food supplements. We conclude that analyzing some perspectives on structural modifications and preparation methods could potentially influence future applications of CS in medical and biomaterial research.

Indexed as

Biocompatible MaterialsChondroitin SulfatesAnimalsDietary SupplementsFermentationPolysaccharidesBiocompatible MaterialsChondroitin SulfatesPolysaccharideschondroitin sulfatefunction and applicationpreparationproperty

Identifiers

PMID37894574
PMCPMC10609508
OpenAlexW4387653677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.