Evidence map›Paper›PMID 37894459›Full record

ReviewCancers2023

Radiosurgery for Brain Metastases: Challenges in Imaging Interpretation after Treatment.

Andrea Romano, Giulia Moltoni, Antonella Blandino, Serena Palizzi, Allegra Romano, Giulia de Rosa, Lara De Blasi Palma, Cristiana Monopoli, Alessia Guarnera, Giuseppe Minniti and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Auxiliary Value of [Cancers · 2025
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrea RomanoNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.
Giulia MoltoniNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.ORCID 0000-0003-0149-9918
Antonella BlandinoNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.
Serena PalizziNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.
Allegra RomanoNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.
Giulia de RosaNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.
Lara De Blasi PalmaNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.
Cristiana MonopoliNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.
Alessia GuarneraNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.ORCID 0000-0001-5529-7575
Giuseppe MinnitiDepartment of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, 00138 Rome, Italy.ORCID 0000-0003-1239-1603
Alessandro BozzaoNESMOS Department, U.O.C. Neuroradiology "Sant'Andrea" University Hospital, 00189 Rome, Italy.ORCID 0000-0002-8865-0723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotactic radiosurgery (SRS) has transformed the management of brain metastases by achieving local tumor control, reducing toxicity, and minimizing the need for whole-brain radiation therapy (WBRT). This review specifically investigates radiation-induced changes in patients treated for metastasis, highlighting the crucial role of magnetic resonance imaging (MRI) in the evaluation of treatment response, both at very early and late stages. The primary objective of the review is to evaluate the most effective imaging techniques for assessing radiation-induced changes and distinguishing them from tumor growth. The limitations of conventional imaging methods, which rely on size measurements, dimensional criteria, and contrast enhancement patterns, are critically evaluated. In addition, it has been investigated the potential of advanced imaging modalities to offer a more precise and comprehensive evaluation of treatment response. Finally, an overview of the relevant literature concerning the interpretation of brain changes in patients undergoing immunotherapies is provided.

Indexed as

brain metastasisimmunotherapymagnetic resonance imagingradiation necrosisstereotactic radiosurgery

Identifiers

PMID37894459
PMCPMC10605307

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.