Evidence map›Paper›PMID 37894366›Full record

ArticleCancers2023

A Phase II Study of Osimertinib in Patients with Advanced-Stage Non-Small Cell Lung Cancer following Prior Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR TKI) Therapy with EGFR and T790M Mutations Detected in Plasma Circulating Tumour DNA (PLASMA Study).

Yvonne L E Ang, Xiaotian Zhao, Thanyanan Reungwetwattana, Byoung-Chul Cho, Bin-Chi Liao, Rebecca Yeung, Herbert H Loong, Dong-Wan Kim, James Chih-Hsin Yang, Sun Min Lim and 10 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 6 countries.

Yvonne L E AngDepartment of Haematology-Oncology, National University Cancer Institute, Singapore 119074, Singapore.
Xiaotian ZhaoGeneseeq Research Institute, Geneseeq Technology Inc., Nanjing 210032, China.ORCID 0000-0003-3823-3232
Thanyanan ReungwetwattanaDivision of Medical Oncology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Byoung-Chul ChoDivision of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Bin-Chi LiaoDepartment of Oncology, National Taiwan University Hospital, Taipei 100229, Taiwan.
Rebecca YeungClinical Oncology Department, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.
Herbert H LoongDepartment of Clinical Oncology, The Chinese University of Hong Kong, Central Ave, Hong Kong.ORCID 0000-0002-6607-1106
Dong-Wan KimSeoul National University College of Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.
James Chih-Hsin YangDepartment of Oncology, National Taiwan University Hospital, Taipei 100229, Taiwan.
Sun Min LimDivision of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Myung-Ju AhnDivision of Haematology-Oncology, Samsung Medical Center, Seoul 06351, Republic of Korea.
Se-Hoon LeeDivision of Haematology-Oncology, Samsung Medical Center, Seoul 06351, Republic of Korea.
Thitiporn SuwatanapongchedDivision of Diagnostic Radiology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Kanchaporn KongchauyClinical Research Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Qiuxiang OuGeneseeq Research Institute, Geneseeq Technology Inc., Nanjing 210032, China.
Ruoying YuGeneseeq Research Institute, Geneseeq Technology Inc., Nanjing 210032, China.
Bee Choo TaiSaw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore.
Boon Cher GohDepartment of Haematology-Oncology, National University Cancer Institute, Singapore 119074, Singapore.
Tony S K MokDepartment of Clinical Oncology, The Chinese University of Hong Kong, Central Ave, Hong Kong.
Ross A SooDepartment of Haematology-Oncology, National University Cancer Institute, Singapore 119074, Singapore.
Mahidol University · THNational University Cancer Institute, Singapore · SGChinese University of Hong Kong · HKNational Taiwan University · TWSamsung Medical Center · KRYonsei University · KRNational University of Singapore · SGPamela Youde Nethersole Eastern Hospital · CNSeoul National University Hospital · KR

Funding

AstraZeneca (Singapore) ESR- 15-10932National Medical Research Council NMRC//MOHIAFCat1/0047/2016
6 · The paper itself

Abstract

Epidermal growth factor receptor (

Indexed as

circulating tumour DNAEGFR T790M mutationsmechanisms of resistancenext-generation sequencingOsimertinib

Identifiers

PMID37894366
PMCPMC10605750
OpenAlexW4387671462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.