Evidence map›Paper›PMID 37894351›Full record

ReviewCancers2023

The Influence of the Microbiome on Urological Malignancies: A Systematic Review.

Joao G Porto, Maria Camila Suarez Arbelaez, Brandon Pena, Archan Khandekar, Ankur Malpani, Bruno Nahar, Sanoj Punnen, Chad R Ritch, Mark L Gonzalgo, Dipen J Parekh and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Joao G PortoDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-6495-1054
Maria Camila Suarez ArbelaezDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Brandon PenaDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Archan KhandekarDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0003-3177-3439
Ankur MalpaniDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Bruno NaharDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Sanoj PunnenDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Chad R RitchDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Mark L GonzalgoDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Dipen J ParekhDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Robert MarcovichDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Hemendra N ShahDesai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microbiome, once considered peripheral, is emerging as a relevant player in the intricate web of factors contributing to cancer development and progression. These often overlooked microorganisms, in the context of urological malignancies, have been investigated primarily focusing on the gut microbiome, while exploration of urogenital microorganisms remains limited. Considering this, our systematic review delves into the complex role of these understudied actors in various neoplastic conditions, including prostate, bladder, kidney, penile, and testicular cancers. Our analysis found a total of 37 studies (prostate cancer 12, bladder cancer 20, kidney cancer 4, penile/testicular cancer 1), revealing distinct associations specific to each condition and hinting at potential therapeutic avenues and future biomarker discoveries. It becomes evident that further research is imperative to unravel the complexities of this domain and provide a more comprehensive understanding.

Indexed as

bladder cancerkidney cancermicrobiomepenile cancerprostate cancertesticular cancer

Identifiers

PMID37894351
PMCPMC10605095
OpenAlexW4387638496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.