Evidence map›Paper›PMID 37894251›Full record

ArticleMicroorganisms2023

Loss of Biliverdin Reductase Increases Oxidative Stress in the Cyanobacterium

Wendy M Schluchter, Courtney H Babin, Xindi Liu, Amori Bieller, Gaozhong Shen, Richard M Alvey, Donald A Bryant

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wendy M SchluchterDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Courtney H BabinDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.ORCID 0000-0002-3870-6135
Xindi LiuDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Amori BiellerDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Gaozhong ShenDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-2801-591X
Richard M AlveyDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-1514-2744
Donald A BryantDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-2782-5988
University of New Orleans · USPennsylvania State University · US

Funding

REGULATION OF BILIPROTEIN IN CYANOBACTERIAR01GM031625 · NIGMS · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI BRYANT, DONALD A · 1985 to 2002
$797k
NIH HHS GM-31625
6 · The paper itself

Abstract

Oxygenic photosynthesis requires metal-rich cofactors and electron-transfer components that can produce reactive oxygen species (ROS) that are highly toxic to cyanobacterial cells. Biliverdin reductase (BvdR) reduces biliverdin IXα to bilirubin, which is a potent scavenger of radicals and ROS. The enzyme is widespread in mammals but is also found in many cyanobacteria. We show that a previously described

Indexed as

antioxidantbilirubinbiliverdinbiliverdin reductasecyanobacteriaphotosynthesisphycobiliproteinsreactive oxygen speciesredox cycle

Identifiers

PMID37894251
PMCPMC10608806
OpenAlexW4387811320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.