Evidence map›Paper›PMID 37894234›Full record

ArticleMicroorganisms2023

Prevalence and Risk Factors for Hepatitis E Virus in Wild Boar and Red Deer in Portugal.

Humberto Pires, Luís Cardoso, Ana Patrícia Lopes, Maria da Conceição Fontes, Sérgio Santos-Silva, Manuela Matos, Cristina Pintado, Luís Figueira, Ana Cristina Matos, João Rodrigo Mesquita and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Review
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  7. Article
  8. Hunting for Answers: AssessingPathogens (Basel, Switzerland) · 2024
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Humberto PiresPolytechnic Institute of Castelo Branco, 6001-909 Castelo Branco, Portugal.
Luís CardosoAnimal and Veterinary Research Centre (CECAV), Department of Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0002-6145-7560
Ana Patrícia LopesAnimal and Veterinary Research Centre (CECAV), Department of Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.
Maria da Conceição FontesAnimal and Veterinary Research Centre (CECAV), Department of Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0002-8913-5504
Sérgio Santos-SilvaSchool of Medicine and Biomedical Sciences (ICBAS), Porto University, 4050-313 Porto, Portugal.ORCID 0000-0001-9742-5643
Manuela MatosCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0002-9584-6636
Cristina PintadoPolytechnic Institute of Castelo Branco, 6001-909 Castelo Branco, Portugal.ORCID 0000-0001-5433-4258
Luís FigueiraResearch Center for Natural Resources, Environment and Society, Polytechnic Institute of Castelo Branco, 6001-909 Castelo Branco, Portugal.
Ana Cristina MatosPolytechnic Institute of Castelo Branco, 6001-909 Castelo Branco, Portugal.ORCID 0000-0001-9709-862X
João Rodrigo MesquitaSchool of Medicine and Biomedical Sciences (ICBAS), Porto University, 4050-313 Porto, Portugal.ORCID 0000-0001-8769-8103
Ana Cláudia CoelhoAnimal and Veterinary Research Centre (CECAV), Department of Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0002-7196-4179
University of Trás-os-Montes and Alto Douro · PTPolytechnic Institute of Castelo Branco · PTUniversidade do Porto · PT

Funding

Fundação para a Ciência e Tecnologia scholarship 2021.09461.BD contract through the Maria de Sousa-2021 programFundação para a Ciência e Tecnologia UIDP/00772/2020 and LA/P/0059/2020
6 · The paper itself

Abstract

Hepatitis E virus (HEV) is a zoonotic foodborne virus with an annual infection prevalence of 20 million human cases, which seriously affects public health and economic development in both developed and developing countries. To better understand the epidemiology of HEV in Central Portugal, a cross-sectional study was conducted from 2016 to 2023 with sera samples from wild ungulates. The seroprevalence and risk factors for HEV seropositivity were evaluated in the present study. Specifically, antibodies against HEV were determined by a commercial enzyme-linked immune-sorbent assay (ELISA). Our results show that in the 650 sera samples collected from 298 wild red deer and 352 wild boars in Portugal, 9.1% red deer and 1.7% wild boar were positive for antibodies to HEV. Regarding age, the seropositivity in juvenile wild ungulates was 1.3%, whereas it was 7.2% in adults. Logistic regression models investigated risk factors for seropositivity. The odds of being seropositive was 3.6 times higher in adults than in juveniles, and the risk was 4.2 times higher in red deer than in wild boar. Both wild ungulate species were exposed to HEV. The higher seroprevalence in red deer suggests that this species may make a major contribution to the ecology of HEV in Central Portugal. Further research is needed to understand how wildlife affects the epidemiology of HEV infections in Portugal.

Indexed as

ELISAhepatitis E virusPortugalred deerrisk factorswild boar

Identifiers

PMID37894234
PMCPMC10609178
OpenAlexW4387706998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.