ArticleMicroorganisms2023
Abnormal Development of Microbiota May Be a Risk Factor for Febrile Urinary Tract Infection in Infancy.
Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Microbiome and metabolomics insights into pediatric urinary tract infection: a narrative review.Childhood kidney diseases · 2026Review
- Consequences of host-microbiome interactions in preterm infants.Infection and immunity · 2025Review
- Exploring Childhood Lower Urinary Tract Symptoms (LUTS), Urinary Tract Infections (UTIs) and the Microbiome-A Systematic Review.Life (Basel, Switzerland) · 2025Review
- Fecal microbiome composition in neonates with or without urinary tract infection.Pediatric nephrology (Berlin, Germany) · 2025Article
- Metagenomic signatures of extraintestinal bacterial infection in the febrile term infant gut microbiome.Microbiome · 2025Article
- Role of Gut and Urinary Microbiome in Children with Urinary Tract Infections: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Recurrent urinary tract infections and psychological burden: mechanisms and integrative perspectives.Frontiers in medicine · 2025Review
- Urinary Tract Infection in Children: An Up-To-Date Study.Biomedicines · 2024Review
- Intrapartum antibiotic exposure and infectious diseases in childhood - a population-based cohort study.EBioMedicine · 2024Article
- Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Febrile urinary tract infection (fUTI) is common in infants, but specific risk factors for developing it remain unclear. As most fUTIs are caused by ascending infections of intestinal bacteria, dysbiosis-an imbalance in gut microbial communities-may increase fUTI risk. This study was conducted to test the hypothesis that abnormal development of gut microbiota during infancy increases the risk of developing fUTI. Stool samples were collected from 28 infants aged 3-11 months with first-onset fUTI (fUTI group) and 51 healthy infants of the same age (HC group). After bacterial DNA extraction, 16S rRNA expression was measured and the diversity of gut microbiota and constituent bacteria were compared between the two groups. The alpha diversity of gut microbiota (median Shannon index and Chao index) was significantly lower in the fUTI group (3.0 and 42.5) than in the HC group (3.7 and 97.0;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.