Evidence map›Paper›PMID 37894161›Full record

ArticleMicroorganisms2023

Gut Microbiome and Lipidome Signatures in Irritable Bowel Syndrome Patients from a Low-Income, Food-Desert Area: A Pilot Study.

Nikita Paripati, Lauren Nesi, John D Sterrett, Lamya'a M Dawud, Lyanna R Kessler, Christopher A Lowry, Lark J Perez, Joshua DeSipio, Sangita Phadtare

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Effects ofInternational journal of molecular sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Nikita ParipatiDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.
Lauren NesiDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.ORCID 0000-0001-8337-382X
John D SterrettDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80309, USA.ORCID 0000-0002-0931-7181
Lamya'a M DawudDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80309, USA.ORCID 0000-0003-1810-4927
Lyanna R KesslerDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80309, USA.ORCID 0000-0002-0021-7969
Christopher A LowryDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80309, USA.ORCID 0000-0003-3920-5575
Lark J PerezDepartment of Chemistry and Biochemistry, Rowan University, Glassboro, NJ 08028, USA.
Joshua DeSipioDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.
Sangita PhadtareDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.ORCID 0000-0002-4388-6150
University of Colorado Boulder · USCooper Medical School of Rowan University · USCooper University Hospital · USDetroit Medical Center · USRowan University · US

Funding

Rowan Inspira grant (Internal) 59228-66000
6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is a common gastroenterological disorder with triggers such as fructose. We showed that our IBS patients suffering from socioeconomic challenges have a significantly high consumption of high-fructose corn syrup (HFCS). Here, we characterize gut microbial dysbiosis and fatty acid changes, with respect to IBS, HFCS consumption, and socioeconomic factors. Fecal samples from IBS patients and healthy controls were subjected to microbiome and lipidome analyses. We assessed phylogenetic diversity and community composition of the microbiomes, and used linear discriminant analysis effect size (LEfSe), analysis of compositions of microbiomes (ANCOM) on highly co-occurring subcommunities (modules), least absolute shrinkage and selection operator (LASSO) on phylogenetic isometric log-ratio transformed (PhILR) taxon abundances to identify differentially abundant taxa. Based on a Procrustes randomization test, the microbiome and lipidome datasets correlated significantly (

Indexed as

dysbiosisgut microbiomehigh-fructose corn syrupirritable bowel syndromelipidome

Identifiers

PMID37894161
PMCPMC10609137
OpenAlexW4387399697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.