Evidence map›Paper›PMID 37894148›Full record

ArticleMicroorganisms2023

Unveiling Rare Pathogens and Antibiotic Resistance in Tanzanian Cholera Outbreak Waters.

Vito Baraka, Tilde Andersson, Geofrey Makenga, Filbert Francis, Daniel T R Minja, Sören Overballe-Petersen, Man-Hung Eric Tang, Kurt Fuursted, Rolf Lood

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vito BarakaTanga Centre, National Institute for Medical Research, Tanga P.O. Box 5004, Tanzania.ORCID 0000-0001-9694-9293
Tilde AnderssonDepartment of Clinical Sciences, Lund University, 221 84 Lund, Sweden.ORCID 0000-0001-8168-5002
Geofrey MakengaTanga Centre, National Institute for Medical Research, Tanga P.O. Box 5004, Tanzania.
Filbert FrancisTanga Centre, National Institute for Medical Research, Tanga P.O. Box 5004, Tanzania.
Daniel T R MinjaTanga Centre, National Institute for Medical Research, Tanga P.O. Box 5004, Tanzania.ORCID 0000-0001-6159-4664
Sören Overballe-PetersenBacterial Reference Center, Statens Serum Institut, 2300 Copenhagen, Denmark.
Man-Hung Eric TangDepartment of Bacteria, Statens Serum Institut, Parasites and Fungi, 2300 Copenhagen, Denmark.ORCID 0000-0002-3483-0219
Kurt FuurstedBacterial Reference Center, Statens Serum Institut, 2300 Copenhagen, Denmark.
Rolf LoodDepartment of Clinical Sciences, Lund University, 221 84 Lund, Sweden.

Funding

Innovation Fund Denmark 7044-00005BSwedish Research Council Formas 2017-00100
6 · The paper itself

Abstract

The emergence of antibiotic resistance is a global health concern. Therefore, understanding the mechanisms of its spread is crucial for implementing evidence-based strategies to tackle resistance in the context of the One Health approach. In developing countries where sanitation systems and access to clean and safe water are still major challenges, contamination may introduce bacteria and bacteriophages harboring antibiotic resistance genes (ARGs) into the environment. This contamination can increase the risk of exposure and community transmission of ARGs and infectious pathogens. However, there is a paucity of information on the mechanisms of bacteriophage-mediated spread of ARGs and patterns through the environment. Here, we deploy Droplet Digital PCR (ddPCR) and metagenomics approaches to analyze the abundance of ARGs and bacterial pathogens disseminated through clean and wastewater systems. We detected a relatively less-studied and rare human zoonotic pathogen,

Indexed as

antibiotic resistancebacteriophagecholeraESBLmicrobiotaOne Healthtransductionwaterzoonotic pathogen

Identifiers

PMID37894148
PMCPMC10609457

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.