Evidence map›Paper›PMID 37894065›Full record

ReviewMicroorganisms2023

Microbiota Transplant and Gynecological Disorders: The Bridge between Present and Future Treatments.

Serena Martinelli, Giulia Nannini, Fabio Cianchi, Fabio Staderini, Francesco Coratti, Amedeo Amedei

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Microbiome and chronic pelvic pain in women: a mini-review.Human reproduction (Oxford, England) · 2026
    Review
  2. Vaginal Microbiota and Pelvic Floor Dysfunction: Mechanistic Insights and Therapeutic Implications.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  3. Review
  4. Review
  5. Progress in interventions for vaginal microecology.Frontiers in cellular and infection microbiology · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Therapeutic potential of microbiome modulation in reproductive cancers.Medical oncology (Northwood, London, England) · 2025
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Women health and microbiota: Different aspects of well-being.World journal of gastroenterology · 2024
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Serena MartinelliDepartment of Clinical and Experimental Medicine, University of Florence, 50139 Florence, Italy.ORCID 0000-0003-4992-2252
Giulia NanniniDepartment of Clinical and Experimental Medicine, University of Florence, 50139 Florence, Italy.
Fabio CianchiDepartment of Clinical and Experimental Medicine, University of Florence, 50139 Florence, Italy.ORCID 0000-0002-6936-8693
Fabio StaderiniDepartment of Clinical and Experimental Medicine, University of Florence, 50139 Florence, Italy.ORCID 0000-0002-2438-2563
Francesco CorattiDepartment of Clinical and Experimental Medicine, University of Florence, 50139 Florence, Italy.
Amedeo AmedeiDepartment of Clinical and Experimental Medicine, University of Florence, 50139 Florence, Italy.ORCID 0000-0002-6797-9343
University of Florence · ITAzienda Ospedaliero-Universitaria Careggi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal microbiota transplantation (FMT) is a procedure that involves transferring fecal bacteria from a healthy donor to a patients' intestines to restore gut-immunity homeostasis. While FMT was primarily supposed to treat gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome-and especially Clostridium difficile infection (currently the only used as clinical treatment)-recent research has suggested that it may also become a potential treatment for gynecological disorders, including endometriosis and polycystic ovary syndrome (PCOS). On the contrary, vaginal microbiota transplantation (VMT) is a newer and less commonly used procedure than the FMT approach, and its potential applications are still being explored. It involves direct grafting of the entire vaginal microbiota of healthy women into the vaginal tract of patients to easily rebuild the local microbiota environment, restoring vaginal eubiosis and relieving symptoms. Like FMT, VMT is thought to have potential in treating different microbiota-related conditions. In fact, many gynecological disorders, such as bacterial vaginosis and vulvovaginal candidiasis, are thought to be caused by an imbalance in the vaginal microbiota. In this review, we will summarize the development, current challenges, and future perspectives of microbiota transplant, with the aim of exploring new strategies for its employment as a promising avenue for treating a broad range of gynecological diseases.

Indexed as

gynecological disordersmicrobiota transplantationvaginal microbiota

Identifiers

PMID37894065
PMCPMC10609601
OpenAlexW4387101585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.