Evidence map›Paper›PMID 37894049›Full record

ArticleMicroorganisms2023

Supporting Clinical Decisions with Rapid Molecular Diagnostic Pneumonia Panel in Pediatric Intensive Care Unit: Single Center Experience in Turkiye.

Gurkan Bozan, Yalcin Kara, Eylem Kiral, Mahmut Can Kizil, Ebru Kacmaz, Tercan Us, Gul Durmaz, Omer Kilic, Ener Cagri Dinleyici

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gurkan BozanPediatric Intensive Care Unit, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.ORCID 0000-0001-5041-8892
Yalcin KaraPediatric Infectious Disease Unit, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.
Eylem KiralPediatric Intensive Care Unit, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.
Mahmut Can KizilPediatric Infectious Disease Unit, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.
Ebru KacmazPediatric Intensive Care Unit, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.
Tercan UsDepartment of Microbiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.
Gul DurmazDepartment of Microbiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.
Omer KilicPediatric Infectious Disease Unit, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.ORCID 0000-0003-0168-4080
Ener Cagri DinleyiciPediatric Intensive Care Unit, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Türkiye.ORCID 0000-0002-0339-0134

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLower respiratory tract infections are the leading cause of morbidity and mortality in children worldwide. It is crucial to promptly conduct diagnostic investigations in order to determine the microbiological cause of pneumonia, since this is necessary to ensure the appropriate delivery of antibiotic therapy to each individual patient. We evaluated the results of a rapid molecular diagnostic pneumonia panel in children with LRTI in a pediatric intensive care unit (PICU). PATIENTS AND

methodsRapid molecular diagnostic pneumonia panel (BioFire

resultsAt least one bacterial pathogen was detected in 57 cases. A total of 77% of children had underlying conditions. A total of 70.4% of children needed invasive mechanical ventilation and 54.4% had ventilator-associated pneumonia.

conclusionsThe utilization of the FA-PP has some beneficial effects, including more prompt delivery of findings compared to conventional approaches. Additionally, this approach enables the identification of resistance profiles in children diagnosed with pneumonia in the PICU. Consequently, these test results facilitate the organization of antibiotic treatment strategies, including escalation and de-escalation approaches. The detection of resistance patterns was exclusively determined via the implementation of molecular testing, prompting a reevaluation of the isolation technique in accordance with the obtained data.

Indexed as

antibiotic resistancepediatric intensive care unitpneumoniarapid molecular diagnostic panelventilator-associated pneumonia

Identifiers

PMID37894049
PMCPMC10609279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.