Evidence map›Paper›PMID 37893926›Full record

ArticleAnimals : an open access journal from MDPI2023

Fibroblast Growth Factor-23 (FGF-23) in Dogs-Reference Interval and Correlation with Hematological and Biochemical Parameters.

Sandra Lapsina, Nicole Nagler, Simon Franz Müller, Annette Holtdirk, Tanja Kottmann, Elisabeth Müller, Ingo Schäfer

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sandra LapsinaLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.ORCID 0000-0001-8635-1327
Nicole NaglerLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.
Simon Franz MüllerLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.ORCID 0000-0002-5429-0088
Annette HoltdirkDr. MED. Kottmann-Clinical Research Organization, Beverstraße 64, 59077 Hamm, Germany.
Tanja KottmannDr. MED. Kottmann-Clinical Research Organization, Beverstraße 64, 59077 Hamm, Germany.
Elisabeth MüllerLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.
Ingo SchäferLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.ORCID 0000-0001-9264-6607
Laboklin (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast growth factor-23 (FGF-23) is a phosphaturic hormone used to monitor chronic kidney disease (CKD) in humans. The aims of this study were (1) to determine the intra- and interassay precision of the FGF-23 concentrations in dogs as measured via the Kainos ELISA FGF-23 kit, (2) to calculate a reference interval, and (3) to assess the correlation of the FGF-23 concentration with the hematological and biochemical parameters. The coefficient of variation was below 15% for both the intra- and interassay precision, indicating good reproducibility. The reference interval ranged between 95.8 (90% confidence interval: 44.6; 139.2) and 695.1 pg/mL (598.7; 799.1) based on 136 clinically healthy dogs, classified as such according to the information of treating veterinarians as well as the unremarkable results of hematology and biochemistry. The FGF-23 concentration differed significantly between dogs aged <9 and ≥9 years (

Indexed as

caninechronic kidney diseaseclinical pathologyFGF-23renal

Identifiers

PMID37893926
PMCPMC10603748
OpenAlexW4387618207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.