Evidence map›Paper›PMID 37893898›Full record

ArticleAnimals : an open access journal from MDPI2023

Intestinal Microbiome in Dogs with Chronic Hepatobiliary Disease: Can We Talk about the Gut-Liver Axis?

Verena Habermaass, Daniela Olivero, Eleonora Gori, Chiara Mariti, Erika Longhi, Veronica Marchetti

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Understanding the diversity and roles of the canine gut microbiome.Journal of animal science and biotechnology · 2025
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Fecal Bile Acids in Canine Chronic Liver Disease: Results from 46 Dogs.Animals : an open access journal from MDPI · 2024
    Article
  7. Article
  8. Supplementation withAnimals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Verena HabermaassDepartment of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, 56122 Pisa, Italy.ORCID 0000-0003-0340-0192
Daniela OliveroAnalysis Lab BSA Scilvet, Via A. D'Aosta 7, 20129 Milan, Italy.ORCID 0000-0002-6667-7546
Eleonora GoriDepartment of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, 56122 Pisa, Italy.ORCID 0000-0001-8612-5573
Chiara MaritiDepartment of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, 56122 Pisa, Italy.ORCID 0000-0001-7127-4680
Erika LonghiAnalysis Lab Labospace, Via Apelle 41, 20128 Milan, Italy.ORCID 0000-0003-1810-7861
Veronica MarchettiDepartment of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, 56122 Pisa, Italy.ORCID 0000-0001-6099-6223
University of Pisa · IT

Funding

University of Pisa pra 2020-69
6 · The paper itself

Abstract

The gut-liver axis represents a current topic in human medicine. Extensive research investigates the gut microbiome (GM) modifications in relation to various kinds of chronic hepatobiliary diseases (CHD), with many mechanisms and therapeutical implications recognized. Those aspects in veterinary medicine are still quite unexplored. The aim of the present study was to evaluate GM in dogs diagnosed with CD. Comparison among CHD dogs were made considering some clinical and biochemical variables (lipemia and alanine-aminotransferase activities), presence of cholestasis or endocrine disorders, diet). Sixty-five dogs were prospectively enrolled with clinical and hematobiochemical evaluation and 16S-RNA GM sequencing assessed. Dogs that received antibiotics and/or pre/pro/symbiotics administration were excluded. Deeper GM alteration was observed between dogs with or without ultrasonographic and biochemical cholestatic CHD. Cholestasis was associated with a decrease in several bacterial taxa, including

Indexed as

canine hepatic diseasecanine microbiotadysbiosisgut microbiotahepatopathyliver–gut axis

Identifiers

PMID37893898
PMCPMC10603696
OpenAlexW4387528784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.