ArticleHealthcare (Basel, Switzerland)2023
Relationship between Composite Dietary Antioxidant Index and Aging.
Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Social, psychosocial, and lifestyle determinants of diabetes and prediabetes in US adults before and after COVID-19: a cross-sectional NHANES analysis.Diabetology & metabolic syndrome · 2026Article
- Composite dietary antioxidant index is nonlinearly associated with low muscle mass in the general US population: findings from NHANES 2001-2018.Nutrition journal · 2025Article
- Associations of composite dietary antioxidant index with premature death and all-cause mortality: a cohort study.BMC public health · 2025Article
- Association between composite dietary antioxidant index and rheumatoid arthritis: results from NHANES 2003-2018.International journal of medical sciences · 2025Article
- Impact of dietary antioxidants on female infertility risk: evidence from NHANES.Scientific reports · 2024Article
- Dietary diversity contributes to delay biological aging.Frontiers in medicine · 2024Article
- Linear association of compound dietary antioxidant index with hyperlipidemia: a cross-sectional study.Frontiers in nutrition · 2024Article
- Association between the Composite Dietary Antioxidant Index and severe headache or migraine: results from the National Health and Nutrition Examination Survey.Frontiers in neurology · 2024Article
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2 authors.
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Abstract
backgroundNumerous studies have demonstrated a close relationship between antioxidant-rich diets and comorbidities as well as mortality. However, the relationship between such diets and aging remains unclear. The purpose of this study was to investigate the association between the Composite Dietary Antioxidant Index (CDAI) and aging.
methodsAll participants were from the National Health and Nutrition Examination Survey (NHANES) 2001-2010. Phenotypic age was calculated using a formula and subtracted from the chronological age to determine the aging. When the phenotypic age exceeded the chronological age, it was considered as aging. A weighted logistic regression model was employed to explore the relationship between CDAI and aging. Restricted cubic splines (RCSs) were used to examine the potential nonlinear relationship between them. Subgroup analysis and joint analysis were conducted to explore the effect of modifiers in these relationships.
resultsA total of 19,212 participants (weighted: 165,285,442 individuals) were included in this study. The weighted logistic regression model showed a significant correlation between CDAI and the risk of aging (OR = 0.90, 95% CI: 0.84-0.96). RCS analysis revealed an L-shaped dose-response relationship between CDAI and the risk of aging. Subgroup analysis indicated that the association between CDAI and aging was more pronounced in middle-aged individuals and non-smokers. The joint analysis demonstrated that although smoking accelerated aging among participants, a high CDAI diet could still offset these damages.
conclusionsThe association between high CDAI and reduced risk of aging is particularly significant in young and middle-aged individuals and non-smokers. Consuming foods rich in CDAI components may potentially lower the risk of aging.
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