Evidence map›Paper›PMID 37893488›Full record

ReviewMedicina (Kaunas, Lithuania)2023

Gastritis Cystica Profunda: A Rare Disease, a Challenging Diagnosis, and an Uncertain Malignant Potential: A Case Report and Review of the Literature.

Francesca De Stefano, Giorgio M P Graziano, Jacopo Viganò, Aurelio Mauro, Andrea Peloso, Jacopo Peverada, Raffaele Fellegara, Alessandro Vanoli, Giuseppe G Faillace, Luca Ansaloni

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Francesca De StefanoDepartment of Surgery, Ospedale Citta' di Sesto San Giovanni, 20099 Sesto San Giovanni, Italy.ORCID 0009-0004-1580-3487
Giorgio M P GrazianoUniversity of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-4023-8040
Jacopo ViganòDepartment of General Surgery I, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0002-2319-5475
Aurelio MauroGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0002-8475-5464
Andrea PelosoVisceral Surgery Division, Organ Transplantation Division, University Hospitals of Geneva, Department of Surgery, University of Geneva, 1205 Geneva, Switzerland.
Jacopo PeveradaUniversity of Pavia, 27100 Pavia, Italy.
Raffaele FellegaraUniversity of Pavia, 27100 Pavia, Italy.
Alessandro VanoliAnatomic Pathology Unit, Department of Molecular Medicine, University of Pavia, IRCCS San Matteo Hospital Foundation, 27100 Pavia, Italy.
Giuseppe G FaillaceDepartment of Surgery, Ospedale Citta' di Sesto San Giovanni, 20099 Sesto San Giovanni, Italy.
Luca AnsaloniUniversity of Pavia, 27100 Pavia, Italy.
University of Pavia · ITNuovo Ospedale San Giovanni di Dio · ITPoliclinico San Matteo Fondazione · ITUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastritis cystica profunda (GCP) has been defined as a rare submucosal benign gastric lesion with cystic gland growth. Due to its unclear etiopathogenesis, this lesion is often misdiagnosed and mistaken for other gastric masses. Currently, a standardized treatment for GCP lesions is still missing. Here, we illustrate a case of a patient admitted to our general surgery department for melena and general discomfort. No history of peptic ulcer or gastric surgery was present. Upper GI endoscopy was performed, showing a distal gastric lesion with a small ulceration on the top. CT-scan and endoscopic ultrasound confirmed the presence of the lesion, compatible with a gastric stromal tumor, without showing any eventual metastasis. Surgical gastric resection was performed. Histological findings were diagnostic for GCP, with cistically ectasic submucosal glands, chronic inflammation, eosinophilic infiltration and foveal hyperplasia. GCP is a very exceptional cause of upper-GI bleeding with specific histological features. Its diagnosis as well as its therapy are challenging, resulting in several pitfalls. Even though it is a rare entity, GCP should always be considered in the differential diagnosis of gastric submucosal lesions.

Indexed as

GastritisGastrointestinal NeoplasmsStomach NeoplasmsHumansRare Diseasesectopic gastric glandsendoscopic ultrasoundgastric submucosal lesiongastric surgerygastritis cystica profunda

Identifiers

PMID37893488
PMCPMC10608487
OpenAlexW4387331433

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.