Evidence map›Paper›PMID 37893323›Full record

ArticleMicromachines2023

Numerical Model Validation of the Blood Flow through a Microchannel Hyperbolic Contraction.

Filipe Barbosa, Jorge Dueñas-Pamplona, Cristiano S Abreu, Mónica S N Oliveira, Rui A Lima

Abstract read
In one paragraph

Article in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Filipe BarbosaMechanical Engineering and Resource Sustainability Center (METRICS), University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0003-2971-910X
Jorge Dueñas-PamplonaDepartamento de Ingeniería Energética, Universidad Politécnica de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-6570-6624
Cristiano S AbreuCenter for MicroElectromechanical Systems (CMEMS-UMinho), University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0002-4878-6159
Mónica S N OliveiraJames Weir Fluids Laboratory, Department of Mechanical and Aerospace Engineering, University of Strathclyde, Glasgow G1 1XJ, UK.
Rui A LimaMechanical Engineering and Resource Sustainability Center (METRICS), University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0003-3428-637X

Funding

Fundação para a Ciência e Tecnologia 2022.06207.PTDC
6 · The paper itself

Abstract

A computational fluid dynamics (CFD) model of blood flow through hyperbolic contraction with a discrete phase model (DPM) was experimentally validated. For this purpose, the positions and velocities of red blood cells (RBCs) flowing in a microchannel with hyperbolic contraction were experimentally assessed using image analysis techniques, and were subsequently compared with the numerical results. The numerically and experimentally obtained velocity fields were in good agreement, with errors smaller than 10%. Additionally, a nearly constant strain rate was observed in the contraction region, which can be attributed to the quasilinear increase in the velocity along the hyperbolic contraction. Therefore, the numerical technique used was validated due to the close similarity between the numerically and experimentally obtained results. The tested CFD model can be used to optimize the microchannel design by minimizing the need to fabricate prototypes and evaluate them experimentally.

Indexed as

blood flowexperimental validationhyperbolic contractionmicrofluidicsnumerical modeling

Identifiers

PMID37893323
PMCPMC10608998

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.