Evidence map›Paper›PMID 37893180›Full record

ArticleBiomedicines2023

Aberrant Immune Features after Recovery from COVID-19 in Patients with Systemic Lupus Erythematosus and Other Autoimmune Diseases.

Siyue Yu, Hao Li, Kai Zhang, Gong Cheng, Yifan Wang, Yuan Jia, Linchong Su, Yuebo Jin, Miao Shao, Jing He

Abstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Siyue YuDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0001-7360-2406
Hao LiDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Kai ZhangDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Gong ChengDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Yifan WangDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Yuan JiaDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Linchong SuHubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Hubei Minzu University, Enshi 430074, China.
Yuebo JinDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Miao ShaoDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Jing HeDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.

Funding

Beijing sci-Tech Program Z191100006619114National Key R&D Program of China 2022YFE0131700National Natural Science Foundation of China 32000639National Natural Science Foundation of China 82071813National Natural Science Foundation of China 8227183
6 · The paper itself

Abstract

Considering the large number of individuals who have already been infected and may have reinfection, the post-infection effects of COVID-19 are of great importance for clinical practice and predicting disease trends. However, our understanding of the potential long-term effects, particularly on immunity, after recovering from COVID-19 remains limited. The aim of this study was to investigate the abnormal immunological factors that contribute to the prolonged immunological effects of COVID-19. Two groups of patients were enrolled in the study, including 11 individuals with various autoimmune diseases (AIDs) and 16 patients diagnosed with systemic lupus erythematosus (SLE). Detailed clinical symptoms were closely monitored, and peripheral mononuclear cells were analyzed using flow cytometry. The clinical status was evaluated using the SLE Disease Activity Index (SLEDAI) and the Clinical Global Impressions (CGI) index. The proportions of follicular T helper cells (Tfh) exhibited significant increases in both cohorts (AID:

Indexed as

broad immune responseCOVID-19immunology mechanismspandemic influenzaregulatory T cell

Identifiers

PMID37893180
PMCPMC10603977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.