Evidence map›Paper›PMID 37893112›Full record

ArticleBiomedicines2023

Bacterial Tyrosinase Inhibition, Hemolytic and Thrombolytic Screening, and In Silico Modeling of Rationally Designed Tosyl Piperazine-Engrafted Dithiocarbamate Derivatives.

Ameer Fawad Zahoor, Freeha Hafeez, Asim Mansha, Shagufta Kamal, Muhammad Naveed Anjum, Zohaib Raza, Samreen Gul Khan, Jamila Javid, Ali Irfan, Mashooq Ahmad Bhat

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Development of new coumarin-piperazine-N-phenylacetamid derivatives as potent tyrosinase inhibitors: In vitro and in silico evaluations.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Synthesis,Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Ameer Fawad ZahoorDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0003-2127-8848
Freeha HafeezDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Asim ManshaDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0001-5659-0562
Shagufta KamalDepartment of Biochemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Muhammad Naveed AnjumDepartment of Applied Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Zohaib RazaDepartment of Chemistry, School of Physical Sciences, University of Adelaide, Adelaide, SA 5000, Australia.ORCID 0000-0001-7789-4530
Samreen Gul KhanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Jamila JavidDepartment of Chemistry, University of Sialkot, Sialkot 51310, Pakistan.
Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-8977-3303
Mashooq Ahmad BhatDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-8426-4692
Government College University, Faisalabad · PKKing Saud University · SAThe University of Adelaide · AUUniversity of Sialkot

Funding

King Saud University, Riyadh, Saudi Arabia RSPD2023R740
6 · The paper itself

Abstract

Piperazine is a privileged moiety that is a structural part of many clinical drugs. Piperazine-based scaffolds have attracted the attention of pharmaceutical and medicinal scientists to develop novel, efficient therapeutic agents owing to their significant and promising biological profile. In the current study, an ecofriendly ultrasonic-assisted synthetic approach was applied to achieve a novel series of 1-tosyl piperazine dithiocarbamate acetamide hybrids

Indexed as

bacterial tyrosinase inhibitiondithiocarbamate derivativeshemolytic activitymolecular dockingthrombolyticTosyl piperazineultrasonic-assisted green synthesis

Identifiers

PMID37893112
PMCPMC10603954
OpenAlexW4387514242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.