Evidence map›Paper›PMID 37892918›Full record

ArticleBioengineering (Basel, Switzerland)2023

Efficient Cytotoxicity of Recombinant Azurin in

Yi Ma, Guanshu Zhu, Lan Feng, Shoujin Jiang, Qi Xiang, Jufang Wang

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Bacterial Minicell-Based Biohybrid Sub-micron Swimmers for Targeted Cargo Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. The Production of Recombinant Azurin fromInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yi MaSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.ORCID 0000-0002-7582-3429
Guanshu ZhuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Lan FengSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Shoujin JiangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Qi XiangInstitute of Biomedicine and Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou 510632, China.ORCID 0000-0001-9790-5823
Jufang WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.ORCID 0000-0002-9908-1001
South China University of Technology · CNJinan University · CN

Funding

Guangdong Key Areas R&D Program 2022B1111080007Natural Science Foundation of Guangdong Province 2022A1515010716
6 · The paper itself

Abstract

Compared to chemical drugs, therapeutic proteins exhibit higher specificity and activity and are generally well-tolerated by the human body. However, the limitations, such as poor stability both in vivo and in vitro as well as difficulties in penetrating cell membranes, hinder their widespread application. To overcome the challenges, a highly efficient protocol was developed and implemented for the recombinant expression of the therapeutic protein azurin and secretion into minicells derived from probiotic

Indexed as

azurincolon cancerminicellsprotein delivery

Identifiers

PMID37892918
PMCPMC10603951
OpenAlexW4387617503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.