Evidence map›Paper›PMID 37892843›Full record

ArticleBioengineering (Basel, Switzerland)2023

Systematic Myostatin Expression Screening Platform for Identification and Evaluation of Myogenesis-Related Phytogenic in Pigs.

Bor-Rung Ou, Ming-Hua Hsu, Ling-Ya Haung, Chuan-Ju Lin, Li-Li Kuo, Yu-Ting Tsai, Yu-Chia Chang, Wen-Yuh Lin, Tsung-Chien Huang, Yun-Chu Wu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Bor-Rung OuDepartment of Animal Science and Biotechnology, Tunghai University, Taichung 407, Taiwan.
Ming-Hua HsuDepartment of Chemistry, National Changhua University of Education, Changhua 500, Taiwan.ORCID 0000-0002-8711-8815
Ling-Ya HaungDepartment of Animal Science and Biotechnology, Tunghai University, Taichung 407, Taiwan.
Chuan-Ju LinAgricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan.
Li-Li KuoAgricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan.
Yu-Ting TsaiDepartment of Animal Science and Biotechnology, Tunghai University, Taichung 407, Taiwan.
Yu-Chia ChangAgricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan.
Wen-Yuh LinDepartment of Animal Science and Biotechnology, Tunghai University, Taichung 407, Taiwan.
Tsung-Chien HuangDepartment of Animal Science and Biotechnology, Tunghai University, Taichung 407, Taiwan.
Yun-Chu WuDepartment of Animal Science and Biotechnology, Tunghai University, Taichung 407, Taiwan.
Jan-Ying YehDepartment of Food Nutrition and Health Biotechnology, Asia University, Taichung 413, Taiwan.
Yu-Chuan LiangAgricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan.
Tunghai University · TWAgricultural Biotechnology Research Center, Academia Sinica · TWAsia University · TWNational Changhua University of Education · TW

Funding

Academia Sinica AS-KPQ-110-ITAR-09Ministry of Science and Technology MOST 106-3114-B-005-001
6 · The paper itself

Abstract

Skeletal muscle growth in livestock impacts meat quantity and quality. Concerns arise because certain feed additives, like beta-agonists, may affect food safety. Skeletal muscle is a specialized tissue consisting of nondividing and multinucleated muscle fibers. Myostatin (MSTN), a protein specific to skeletal muscle, is secreted and functions as a negative regulator of muscle mass by inhibiting the proliferation and differentiation of myoblasts. To enhance livestock muscle growth, phytogenic feed additives could be an alternative as they inhibit MSTN activity. The objective of this study was to establish a systematic screening platform using MSTN activity to evaluate phytogenics, providing scientific evidence of their assessment and potency. In this study, we established a screening platform to monitor myostatin promoter activity in rat L8 myoblasts. Extract of

Indexed as

feed additiveGlycyrrhiza uralensismyogenesismyostatinskeletal muscle

Identifiers

PMID37892843
PMCPMC10604025
OpenAlexW4386995758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.