Evidence map›Paper›PMID 37892836›Full record

ArticleJournal of clinical medicine2023

Dapagliflozin Improved Cardiac Function and Structure in Diabetic Patients with Preserved Ejection Fraction: Results of a Single Centre, Observational Prospective Study.

Marcelino Cortés, Oscar Lorenzo, Jairo Lumpuy-Castillo, Sacramento Martínez-Albaladejo, Mikel Taibo-Urquía, Ana María Pello, Antonio José Bollas, Miguel Orejas, Miguel Ángel Navas, Ester Macia and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Diabetes Mellitus in Acute Coronary Syndrome.Life (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Marcelino CortésCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.ORCID 0000-0002-2304-8547
Oscar LorenzoLaboratory of Diabetes and Vascular Pathology, IIS-Fundación Jiménez Díaz, Universidad Autónoma, 28040 Madrid, Spain.ORCID 0000-0001-5515-6078
Jairo Lumpuy-CastilloLaboratory of Diabetes and Vascular Pathology, IIS-Fundación Jiménez Díaz, Universidad Autónoma, 28040 Madrid, Spain.ORCID 0000-0002-3458-0328
Sacramento Martínez-AlbaladejoLaboratory of Diabetes and Vascular Pathology, IIS-Fundación Jiménez Díaz, Universidad Autónoma, 28040 Madrid, Spain.ORCID 0009-0006-8495-6051
Mikel Taibo-UrquíaCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.ORCID 0000-0003-2404-3657
Ana María PelloCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.
Antonio José BollasCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.ORCID 0000-0003-4612-3949
Miguel OrejasCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.
Miguel Ángel NavasCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.
Ester MaciaCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.
María Esther MartínezCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.
Andrea RuedaCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.ORCID 0000-0001-7611-9081
Jose TuñónCardiology Department, Fundación Jiménez Díaz Hospital, 28040 Madrid, Spain.ORCID 0000-0002-1373-0999
Hospital Universitario Fundación Jiménez Díaz · ESCentro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium-glucose cotransporter inhibitors (SGLT2i) have demonstrated a reduction in cardiovascular events in diabetes and heart failure (HF). The mechanisms underlying this benefit are not well known and data are contradictory. The purpose of this study is to analyse the effect of dapagliflozin on cardiac structure and function in patients with normal ejection fraction. Between October 2020 and October 2021, we consecutively included 31 diabetic patients without prior history of SGLT2i use. In all of them, dapagliflozin treatment was started. At inclusion and during six months of follow-up, different clinical, ECG, analytical, and echocardiographic (standard, 3D, and speckle tracking) variables were recorded. After a follow-up period of 6.6 months, an average reduction of 18 g (

Indexed as

biomarkersdapagliflozinechocardiographysodium-glucose cotransporter type 2 inhibitorsspeckle tracking

Identifiers

PMID37892836
PMCPMC10607224
OpenAlexW4387880791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.