Evidence map›Paper›PMID 37892664›Full record

ReviewJournal of clinical medicine2023

Ten Issues to Update in Nosocomial or Hospital-Acquired Pneumonia: An Expert Review.

Francisco Javier Candel, Miguel Salavert, Angel Estella, Miquel Ferrer, Ricard Ferrer, Julio Javier Gamazo, Carolina García-Vidal, Juan González Del Castillo, Víctor José González-Ramallo, Federico Gordo and 11 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Management of pneumonia by the emergency radiologist.European journal of radiology open · 2026
    Article
  3. Challenges and opportunities in the management of severe pneumonia. Key concepts from the Seventh Annual Meeting of Spanish Experts 2025.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  4. Surveillance of temporal trends and antimicrobial resistance in nosocomial respiratory pathogens, Switzerland, 2007 to 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Therapeutic management of health care-associated pneumonia.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Towards a holistic approach to pulmonary infections. Insights from the Sixth Annual Meeting of Spanish Experts 2024.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Review
  13. Difficult-to-TreatAntibiotics (Basel, Switzerland) · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Candent issues in pneumonia. Reflections from the Fifth Annual Meeting of Spanish Experts 2023.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 18 institutions in 1 country.

Francisco Javier CandelClinical Microbiology and Infectious Diseases, Transplant Coordination, IdISSC & IML Health Research Institutes, Hospital Clínico Universitario San Carlos, 28040 Madrid, Spain.
Miguel SalavertInfectious Diseases Unit, La Fe (IIS) Health Research Institute, Hospital Universitario y Politécnico La Fe, 46026 València, Spain.ORCID 0000-0002-8571-2124
Angel EstellaIntensive Medicine Service, Hospital Universitario de Jerez, 11407 Jerez, Spain.ORCID 0000-0003-0665-557X
Miquel FerrerUVIR, Servei de Pneumologia, Institut Clínic de Respiratori, Hospital Clínic de Barcelona, IDIBAPS, CibeRes (CB06/06/0028), Universitat de Barcelona, 08007 Barcelona, Spain.ORCID 0000-0001-8171-6673
Ricard FerrerIntensive Medicine Service, Hospital Universitario Valle de Hebrón, 08035 Barcelona, Spain.ORCID 0000-0002-4859-4747
Julio Javier GamazoServicio de Urgencias, Hospital Universitario de Galdakao, 48960 Bilbao, Spain.ORCID 0000-0001-9866-4259
Carolina García-VidalInfectious Disease Service, Hospital Clinic, 08036 Barcelona, Spain.ORCID 0000-0002-8915-0683
Juan González Del CastilloEmergency Medicine Service, Hospital Universitario San Carlos, 28040 Madrid, Spain.
Víctor José González-RamalloUnidad de Hospitalización a Domicilio, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Federico GordoIntensive Medicine Service, Hospital Universitario del Henares, 28822 Coslada, Spain.
Manuel Mirón-RubioServicio de Hospitalización a Domicilio, Hospital Universitario de Torrejón, 28850 Torrejón de Ardoz, Spain.
Javier Pérez-PallarésDivision of Respiratory Medicine, Hospital Universitario Santa Lucía, 30202 Cartagena, Spain.ORCID 0000-0001-5246-4876
Cristina PitartDepartment of Clinical Microbiology, ISGlobal, Hospital Clínic-University of Barcelona, CIBERINF, 08036 Barcelona, Spain.ORCID 0000-0002-3083-7915
José Luís Del PozoServicio de Enfermedades Infecciosas, Servicio de Microbiología, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-5402-3334
Paula RamírezIntensive Medicine Service, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0002-7598-3350
Pedro RascadoIntensive Care Unit, Complejo Hospitalario Universitario Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0001-6216-8667
Soledad ReyesNeumology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Patricia Ruiz-GarbajosaMicrobiology Department, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Borja SuberviolaIntensive Medicine Service, Hospital Universitario Marqués de Valdecilla, Instituto de Investigación Sanitaria IDIVAL, 39011 Santander, Spain.
Pablo VidalIntensive Medicine Service, Complexo Hospitalario Universitario de Ourense, 32005 Ourense, Spain.ORCID 0000-0003-0225-9975
Rafael ZaragozaIntensive Care Unit, Hospital Dr. Peset, 46017 Valencia, Spain.ORCID 0000-0002-6593-5486
Hospital Clínic de Barcelona · ESHospital Universitari i Politècnic La Fe · ESBarcelona Institute for Global Health · ESComplejo Hospitalario Universitario de Santiago · ESComplexo Hospitalario Universitario A Coruña · ESHospital Clínico San Carlos · ESHospital de Galdakao · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario del Henares · ESHospital Universitario de Torrejón · ESHospital Universitario Doctor Peset · ESHospital Universitario Ramón y Cajal · ESInstituto de Investigación Marqués de Valdecilla · ESInstituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESNavarre Institute of Health Research · ESSanta Lucía University General Hospital · ESUniversidad de Cádiz · ESVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nosocomial pneumonia, or hospital-acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP) are important health problems worldwide, with both being associated with substantial morbidity and mortality. HAP is currently the main cause of death from nosocomial infection in critically ill patients. Although guidelines for the approach to this infection model are widely implemented in international health systems and clinical teams, information continually emerges that generates debate or requires updating in its management. This scientific manuscript, written by a multidisciplinary team of specialists, reviews the most important issues in the approach to this important infectious respiratory syndrome, and it updates various topics, such as a renewed etiological perspective for updating the use of new molecular platforms or imaging techniques, including the microbiological diagnostic stewardship in different clinical settings and using appropriate rapid techniques on invasive respiratory specimens. It also reviews both Intensive Care Unit admission criteria and those of clinical stability to discharge, as well as those of therapeutic failure and rescue treatment options. An update on antibiotic therapy in the context of bacterial multiresistance, in aerosol inhaled treatment options, oxygen therapy, or ventilatory support, is presented. It also analyzes the out-of-hospital management of nosocomial pneumonia requiring complete antibiotic therapy externally on an outpatient basis, as well as the main factors for readmission and an approach to management in the emergency department. Finally, the main strategies for prevention and prophylactic measures, many of them still controversial, on fragile and vulnerable hosts are reviewed.

Indexed as

diagnosis stewardshipepidemiologyetiologyhealthcare-associated pneumoniahospital at homemanagementnosocomial pneumoniapreventionradiologic findingsreadmissionrescuetherapeutic failurevaccination

Identifiers

PMID37892664
PMCPMC10607368
OpenAlexW4387639028

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.