Evidence map›Paper›PMID 37892640›Full record

ArticleJournal of clinical medicine2023

Reproductive Outcomes of Women with Turner Syndrome Undergoing Oocyte Vitrification: A Retrospective Multicenter Cohort Study.

Sapthami Nadesapillai, Femke Mol, Simone L Broer, Linda B P M Stevens Brentjens, Marieke O Verhoeven, Karst Y Heida, Mariëtte Goddijn, Ron J T van Golde, Annelies M E Bos, Sanne van der Coelen and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Sapthami NadesapillaiDepartment of Obstetrics and Gynecology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Femke MolDepartment of Obstetrics and Gynecology, Amsterdam University Medical Center, Center for Reproductive Medicine, Amsterdam Reproduction & Development Research Institute, University of Amsterdam, 1100 DD Amsterdam, The Netherlands.ORCID 0000-0002-6892-5574
Simone L BroerDepartment of Reproductive Medicine, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Linda B P M Stevens BrentjensDepartment of Obstetrics and Gynecology, Maastricht University Medical Center+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0001-7650-8837
Marieke O VerhoevenDepartment of Obstetrics and Gynecology, Amsterdam University Medical Center, Center for Reproductive Medicine, Amsterdam Reproduction & Development Research Institute, University of Amsterdam, 1100 DD Amsterdam, The Netherlands.
Karst Y HeidaDijklander Hospital, Centrum Voor Kinderwens, 1441 RN Purmerend, The Netherlands.
Mariëtte GoddijnDepartment of Obstetrics and Gynecology, Amsterdam University Medical Center, Center for Reproductive Medicine, Amsterdam Reproduction & Development Research Institute, University of Amsterdam, 1100 DD Amsterdam, The Netherlands.
Ron J T van GoldeDepartment of Obstetrics and Gynecology, Maastricht University Medical Center+, 6229 HX Maastricht, The Netherlands.
Annelies M E BosDepartment of Reproductive Medicine, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Sanne van der CoelenDepartment of Obstetrics and Gynecology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0003-3604-6230
Ronald PeekDepartment of Obstetrics and Gynecology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Didi D M BraatDepartment of Obstetrics and Gynecology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Janielle A E M van der VeldenDepartment of Pediatrics, Amalia's Children's Hospital, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Kathrin FleischerDepartment of Reproductive Medicine, Nij Geertgen Center for Fertility, 5424 SM Elsendorp, The Netherlands.ORCID 0000-0002-2785-5573
Radboud University Nijmegen · NLUniversity of Amsterdam · NLMaastricht University · NLUniversity Medical Center Utrecht · NLDe Kinderkliniek · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTurner syndrome (TS) is accompanied with premature ovarian insufficiency. Oocyte vitrification is an established method to preserve fertility. However, data on the oocyte yield in women with TS who vitrify their oocytes and the return rate to utilize the oocytes are scarce.

methodsRetrospective multicenter cohort study. Data was collected from medical records of women with TS who started oocyte vitrification between 2010 and 2021.

resultsThirty-three women were included. The median cumulative number of vitrified oocytes was 20 per woman. Complications occurred in 4% of the cycles. Significant correlations were found between the cumulative number of vitrified oocytes and AMH (r = 0.54 and

conclusionsOocyte vitrification is a feasible fertility preservation option for women with TS, particularly in those with 46,XX cell lines or sufficient ovarian reserve. Multiple stimulation cycles are recommended to reach an adequate number of vitrified oocytes for pregnancy. It is too early to draw conclusions about the utilization of vitrified oocytes in women with TS.

Indexed as

fertility preservationoocyte vitrificationpregnancyTurner syndrome

Identifiers

PMID37892640
PMCPMC10607490
OpenAlexW4387614472

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.