Evidence map›Paper›PMID 37892635›Full record

ArticleJournal of clinical medicine2023

Red Cell Distribution Width Association with Subclinical Cardiovascular Disease in Patients with Rheumatoid Arthritis.

Marta González-Sierra, Alejandro Romo-Cordero, Juan C Quevedo-Abeledo, Adrián Quevedo-Rodríguez, Fuensanta Gómez-Bernal, Antonia de Vera-González, Raquel López-Mejías, Candelaria Martín-González, Miguel Ángel González-Gay, Iván Ferraz-Amaro

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Marta González-SierraDivision of Hospitalization-at-Home, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Alejandro Romo-CorderoDivision of Internal Medicine, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Juan C Quevedo-AbeledoDivision of Rheumatology, Hospital Universitario Dr. Negrín, 35010 Las Palmas de Gran Canaria, Spain.ORCID 0000-0003-0398-9072
Adrián Quevedo-RodríguezDivision of Rheumatology, Hospital Universitario Dr. Negrín, 35010 Las Palmas de Gran Canaria, Spain.
Fuensanta Gómez-BernalDivision of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.ORCID 0000-0002-8597-1943
Antonia de Vera-GonzálezDivision of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Raquel López-MejíasEpidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Hospital Universitario Marqués de Valdecilla, Instituto de Investigación Sanitaria Marqués de Valdecilla (IDIVAL), 39011 Santander, Spain.ORCID 0000-0003-0548-2689
Candelaria Martín-GonzálezDivision of Internal Medicine, Hospital Universitario de Canarias, 38320 Tenerife, Spain.ORCID 0000-0002-4702-1840
Miguel Ángel González-GayDepartment of Medicine and Psychiatry, Universidad de Cantabria, 39005 Santander, Spain.ORCID 0000-0002-7924-7406
Iván Ferraz-AmaroInternal Medicine Department, Universidad de La Laguna, 38200 Tenerife, Spain.ORCID 0000-0003-0197-5267
Hospital Universitario de Canarias · ESHospital Universitario de Gran Canaria Doctor Negrín · ESUniversidad de La Laguna · ESInstituto de Investigación Marqués de Valdecilla · ESUniversidad de Cantabria · ES

Funding

Instituto de Salud Carlos III PI20/00084
6 · The paper itself

Abstract

Red cell distribution width (RDW) is a measure of the variation in mean corpuscular volume that reflects the degree of anisocytosis on the peripheral blood smear. RDW value variation has been implicated in several disorders including chronic inflammatory processes and cardiovascular (CV) diseases. In the present work, our objective was to study the relationship that RDW has with the characteristics of the disease in patients with rheumatoid arthritis (RA), focusing on CV risk factors and subclinical atherosclerosis. A cross-sectional study was conducted that included 430 patients with RA and 208 controls matched by sex and age. Complete blood count, including RDW, was assessed. Multivariable analysis was performed to analyze the relationship of RDW with RA disease characteristics, subclinical carotid atherosclerosis, and traditional CV factors, including a comprehensive profile of lipid molecules and insulin resistance and beta cell function indices. After multivariable adjustment, the RDW was significantly higher in RA patients compared with controls (beta coefficient 1.0 [95% confidence interval 0.2 to 1.8] %,

Indexed as

cardiovascular diseasered cell distribution widthrheumatoid arthritisSCORE2

Identifiers

PMID37892635
PMCPMC10607716
OpenAlexW4387568769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.