ReviewJournal of clinical medicine2023
Oral Manifestations of Crohn's Disease: A Systematic Review.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Review
- The mouth as a window: A multi-center retrospective study of oral extraintestinal manifestations of IBD and their management.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Case Report: Exploring the link between severe gingivitis and inflammatory bowel disease in a young patient.Frontiers in dental medicine · 2026Article
- Bilateral Lower Lip Swelling as an Early Manifestation of Crohn's Disease in a 16-Year-Old Patient: A Case Report.Case reports in dentistry · 2026Article
- Vegetative pyodermatitis-pyostomatitis in a patient with Crohn's disease: a clinical case report.Diagnostic pathology · 2025Article
- Opportunities and challenges harnessing antigen-specific CD4+ regulatory T cells in inflammatory bowel disease.Frontiers in immunology · 2025Review
- Oral mucosal findings in ambulatory patients with inflammatory bowel disease.Brazilian oral research · 2025Article
- Tonsillar Crohn's Disease.United European gastroenterology journal · 2024Article
- Specific Oral Manifestations in Adults with Crohn's Disease.Journal of clinical medicine · 2024Article
- Eosinophils in Oral Disease: A Narrative Review.International journal of molecular sciences · 2024Review
- Celiac Disease-Related Enamel Defects: A Systematic Review.Journal of clinical medicine · 2024Review
- HIV-Related Oral Mucosa Lesions: A Cross-Sectional Study on a Cohort of Italian Patients.Biomedicines · 2024Article
- A potential brain functional biomarker distinguishing patients with Crohn's disease with different disease stages: a resting-state fMRI study.Frontiers in neuroscience · 2024Article
- From Orofacial Granulomatosis to Crohn's Disease: A Case Report.GE Portuguese journal of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crohn's disease (CD) is a chronic inflammatory intestinal condition that can affect the entire gastrointestinal tract. It is characterized by its clinical heterogeneity and irregularities in its course. The etiology and pathogenesis are not well established, so it is difficult to establish an early diagnosis and an effective treatment plan. The objective of this systematic review was to present a qualitative synthesis of the studies referring to the oral manifestations of CD. This systematic review was carried out following the PRISMA guide. Research was conducted in the Pubmed, Web of Science, Scopus, Scielo, and Cocrahne Library databases on 23 February 2023, and updated on 1 September 2023. Articles published between 2012 and 2023 were selected. Articles that analyzed the oral manifestation of CD patients and met the established search terms. In addition, the quality of all the selected studies was analyzed following the CARE guidelines for case reports and the STROBE scale for observational studies. A total of 19 articles were included in this review that met the inclusion criteria. Regarding the oral manifestation of CD, oral ulcers, angular cheilitis, and gingivitis stand out. Periodontitis and vegetative pyostomatitis were the least representative manifestations. The most prevalent locations were lips, mucosa, and gingivae. Ulcers, gingivitis, and angular cheilitis are the most frequent oral manifestations in patients with CD. Their early identification and possible relationship with the disease are important for an early diagnosis and an adequate treatment plan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.