Evidence map›Paper›PMID 37892573›Full record

ArticleJournal of clinical medicine2023

A Randomized, Double-Blind, Graded Dose-Response Study of Norepinephrine Administration for Prevention of Post-Spinal Hypotension during Elective Cesarean Delivery.

Volkan Baytaş, Süheyla Karadağ Erkoç, Menekşe Özçelik, Derya Gökmen, Ahmet Onat Bermede, Özlem Selvi Can, Asuman Uysalel

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04701190 (Comparison of Different Noradrenaline Protocols to Prevent Post Spinal Hypotension During Elective Caesarean Delivery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04701190 phase4completednot on this map

Comparison of Different Noradrenaline Protocols to Prevent Post Spinal Hypotension During Elective Caesarean Delivery: A Randomised, Double-blind Clinical Trial

TypeinterventionalSponsorAnkara UniversityRan2021 to 2021Enrolled180ConditionsHypotension, Cesarean Section, Anesthesia, SpinalArmsNoradrenalin 10 microgram bolus, Noradrenaline 5 microgram bolus, Noradrenaline 0.1 microgram/kg/minute infusion, Noradrenaline 0.05 microgram/kg/minute infusion, Infusion dosage: 0.075 microgram/kg/minute infusion
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Volkan BaytaşDepartment of Anaesthesiology and ICM, School of Medicine, Ankara University, 06230 Ankara, Türkiye.
Süheyla Karadağ ErkoçDepartment of Anaesthesiology and ICM, School of Medicine, Ankara University, 06230 Ankara, Türkiye.
Menekşe ÖzçelikDepartment of Anaesthesiology and ICM, School of Medicine, Ankara University, 06230 Ankara, Türkiye.
Derya GökmenDepartment of Biostatistics, School of Medicine, Ankara University, 06290 Ankara, Türkiye.
Ahmet Onat BermedeDepartment of Anaesthesiology and ICM, School of Medicine, Ankara University, 06230 Ankara, Türkiye.ORCID 0000-0002-8598-6264
Özlem Selvi CanDepartment of Anaesthesiology and ICM, School of Medicine, Ankara University, 06230 Ankara, Türkiye.
Asuman UysalelDepartment of Anaesthesiology and ICM, School of Medicine, Ankara University, 06230 Ankara, Türkiye.
Ankara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Norepinephrine has been recently introduced for prophylaxis against post-spinal hypotension during cesarean delivery; however, no data are available regarding its optimum dosing scheme. The primary objective of this study is to compare three different infusion and bolus dose combinations of norepinephrine for prophylaxis against post-spinal hypotension during cesarean delivery. This randomized, double-blind study was performed between February 2021 and May 2022. The study protocol was registered at Clinicaltrials.gov with the identification number NCT04701190. A total of 192 parturients were enrolled into this study. Patients were assigned to three groups-Zero-Bolus High-Infusion (Group ZBHI, 0 µg/0.1 µg kg

Indexed as

cesarean deliverynorepinephrineperioperative outcomepost-spinal hypotension

Identifiers

PMID37892573
PMCPMC10607547
OpenAlexW4387502390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.