Evidence map›Paper›PMID 37892482›Full record

ReviewNutrients2023

Synergistic Strategies for Gastrointestinal Cancer Care: Unveiling the Benefits of Immunonutrition and Microbiota Modulation.

Serena Martinelli, Ingrid Lamminpää, Eda Nur Dübüş, Dilara Sarıkaya, Elena Niccolai

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Serena MartinelliDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.ORCID 0000-0003-4992-2252
Ingrid LamminpääDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.ORCID 0009-0006-1724-8821
Eda Nur DübüşDepartment of Nutrition and Dietetics, Gazi University, 06560 Ankara, Turkey.ORCID 0009-0009-0374-5087
Dilara SarıkayaDepartment of Nutrition and Dietetics, Gazi University, 06560 Ankara, Turkey.ORCID 0009-0002-2405-1403
Elena NiccolaiDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.ORCID 0000-0002-9205-8079
University of Florence · ITGazi University · TR

Funding

European Commission H2020-WIDESPREAD-2018-2020/H2020European Union CUP B83C22003920001
6 · The paper itself

Abstract

Gastrointestinal (GI) cancers are a group of highly prevalent malignant tumors affecting the gastrointestinal tract. Globally, one in four cancer cases and one in three cancer deaths are estimated to be GI cancers. They can alter digestive and absorption functions, leading to severe malnutrition which may worsen the prognosis of the patients. Therefore, nutritional intervention and monitoring play a fundamental role in managing metabolic alterations and cancer symptoms, as well as minimizing side effects and increasing the effectiveness of chemotherapy. In this scenario, the use of immunonutrients that are able to modulate the immune system and the modification/regulation of the gut microbiota composition have gained attention as a possible strategy to improve the conditions of these patients. The complex interaction between nutrients and microbiota might contribute to maintaining the homeostasis of each individual's immune system; therefore, concurrent use of specific nutrients in combination with traditional cancer treatments may synergistically improve the overall care of GI cancer patients. This work aims to review and discuss the role of immunonutrition and microbiota modulation in improving nutritional status, postoperative recovery, and response to therapies in patients with GI cancer.

Indexed as

Gastrointestinal NeoplasmsMicrobiotaHumansImmunonutrition DietNutritional Statusgastrointestinal cancersimmunonutrientsimmunonutritionmicrobiotanutritional therapyprobiotics

Identifiers

PMID37892482
PMCPMC10610426
OpenAlexW4387707233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.