Evidence map›Paper›PMID 37892448›Full record

ArticleNutrients2023

Does the Protective Effect of Zinc on Telomere Length Depend on the Presence of Hypertension or Type 2 Diabetes? Results from the Iwaki Health Promotion Project, Japan.

Mahiro Sato, Kyi Mar Wai, Ken Itoh, Yichi Yang, Yuka Uchikawa, Yukihiko Ito, Shigeyuki Nakaji, Kazushige Ihara

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mahiro SatoSchool of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.
Kyi Mar WaiDepartment of Social Medicine, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.ORCID 0000-0001-8755-277X
Ken ItohDepartment of Stress Response Science, Center for Advanced Medical Research, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.ORCID 0000-0002-5518-0729
Yichi YangDepartment of Social Medicine, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.
Yuka UchikawaResearch and Development Division, MiRTeL Company Limited, Hiroshima 734-0001, Japan.
Yukihiko ItoDepartment of Social Medicine, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.
Shigeyuki NakajiDepartment of Social Medicine, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.ORCID 0000-0002-4190-5151
Kazushige IharaDepartment of Social Medicine, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.
Hirosaki University · JP

Funding

Hirosaki University COI accelerating grant JPMJCA2201Japan Science and Technology Agency JPMJCE1302
6 · The paper itself

Abstract

Telomeres, repeated TTAGGG sequences at chromosomal ends, shorten with age and indicate cellular lifespan. Zinc can protect against telomere damage through its anti-oxidative effect. Meanwhile, telomere shortening was correlated with metabolic diseases of hypertension and type 2 diabetes. The objective of this study was to investigate whether the association between zinc and telomere length differs by the presence or absence of hypertension/type 2 diabetes. This is a cross-sectional study with 1064 participants of the Iwaki area, Japan. Multiple linear regression models were performed to test the hypothesis. A higher serum zinc concentration was significantly associated with a longer G-tail length (β = 48.11, 95% confidence intervals [CI]: 25.69, 70.54,

Indexed as

Diabetes Mellitus, Type 2HypertensionCross-Sectional StudiesHumansJapanTelomereZincZincdiabeteshypertensionJapantelomerezinc

Identifiers

PMID37892448
PMCPMC10609662
OpenAlexW4387670780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.